ID A0A5S5C5M0_9BACL Unreviewed; 458 AA.
AC A0A5S5C5M0;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=16S rRNA C967 or C1407 C5-methylase (RsmB/RsmF family) {ECO:0000313|EMBL:TYP73772.1};
GN ORFNames=BCM02_10648 {ECO:0000313|EMBL:TYP73772.1};
OS Paenibacillus methanolicus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=582686 {ECO:0000313|EMBL:TYP73772.1, ECO:0000313|Proteomes:UP000323257};
RN [1] {ECO:0000313|EMBL:TYP73772.1, ECO:0000313|Proteomes:UP000323257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL24 {ECO:0000313|EMBL:TYP73772.1,
RC ECO:0000313|Proteomes:UP000323257};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TYP73772.1}.
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DR EMBL; VNHS01000006; TYP73772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5S5C5M0; -.
DR Proteomes; UP000323257; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21147; RsmF_methylt_CTD1; 1.
DR Gene3D; 2.30.130.60; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR031341; Methyltr_RsmF_N.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR027391; Nol1_Nop2_Fmu_2.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR031340; RsmF_methylt_CI.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807:SF30; 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR Pfam; PF17125; Methyltr_RsmF_N; 1.
DR Pfam; PF13636; Methyltranf_PUA; 1.
DR Pfam; PF17126; RsmF_methylt_CI; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000323257};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 24..297
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 236
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 114..120
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 138
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 183
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 458 AA; 49406 MW; E2FEAAB5F3EBAF4C CRC64;
MRATLPEAYI SQMKQLLGPE SEDFLDSYDQ PRTYGLRINT LKSGVWPSVQ GALTDAFGLA
PIPWCETGLY YDELARPGKH PYHAAGLYYI QEPSAMTAAE LLDVRPGLTV LDLAAAPGGK
TTQIAGKMNG KGLLIANEIH PARAKILSEN VERCGIANAV VANAAPDELS KRFPAFFDRI
MLDAPCSGEG MFRKDEGAVA EWSPSHVAMC AARQADILAH AAAMLKPGGR MVYSTCTFNR
SENEDAMLAF CRLHPEFELV LTERVWPHSA RGEGHFVAVL RRSESAEPLP AAQDRKPGRK
GRQAAAGTAL KSEMALFHDF VRESLPQGIE LAPGEPIRFG DALYWLPHGS ANGRFASADL
QGLKVARPGL HLCDIRKNRA EPSHALAMAL PASAAKWTQS YASDAPEIAA YLRGETLAAA
EDHAGWGLIA VDGLPLGWGK ASAGIVKNHL PKGLRAFK
//
