ID A0A643BPT6_BALPH Unreviewed; 1038 AA.
AC A0A643BPT6;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=E2I00_016820 {ECO:0000313|EMBL:KAB0389976.1};
OS Balaenoptera physalus (Fin whale) (Balaena physalus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=9770 {ECO:0000313|EMBL:KAB0389976.1, ECO:0000313|Proteomes:UP000437017};
RN [1] {ECO:0000313|EMBL:KAB0389976.1, ECO:0000313|Proteomes:UP000437017}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FinWhale-01 {ECO:0000313|EMBL:KAB0389976.1};
RX PubMed=31553763;
RA Westbury M.V., Petersen B., Lorenzen E.D.;
RT "Genomic analyses reveal an absence of contemporary introgressive admixture
RT between fin whales and blue whales, despite known hybrids.";
RL PLoS ONE 14:0-e0222004(2019).
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB0389976.1}.
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DR EMBL; SGJD01006162; KAB0389976.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A643BPT6; -.
DR Proteomes; UP000437017; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
DR Pfam; PF05833; NFACT_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000437017}.
FT DOMAIN 502..612
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 937..1028
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 395..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 271..315
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 459..486
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 726..752
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..826
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..868
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..943
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1038 AA; 118481 MW; EF8D432F13B3E12B CRC64;
MRVNNVYDVD NKTYLIRLQK PDFKATLLLE SGIRIHTTEF EWPKNMMPSS FAMKCRKHLK
SRRLVSAKQL GVDRIVDFQF GSDEAAYHLI IELYDRGNIV LTDYEYLILN ILRFRTDESD
DVKFAVREHY PVDHARAAEP LLTLERLTEI IASAPKGELL KRVLNPLLPC GPALIEHCLI
ENGFSGNVKV DEKFENIEKV LVCLQKAEEY MKTTSNFSGK GYIIQKREIK PSLEVDKPTE
DILTYEEFHP FLFSQHSQCP YIEFESFDKA VDEFYSKIEG QKIDLKALQQ EKQALKKLDN
VRKDHENRLE ALQQAQEIDK LKGELIEMNL QIVDRAIQVV RSALANQIDW TEIGLIVKEA
QAQGDPVANA IKELKLQTNH VTMLLRNPYL LSEEEDDDVD GDISTEKNET EPPKGKKKKQ
KNKQLQKPQK NRPLLIDVDL SLSAYANAKK YYDHKRYAAK KTQKTVEAAE KAFKSAEKKT
KQTLKEVQTV TSIQKARKVF EKFLWFISSE NYLIIGGRDQ QQNEIIVKRY LTPGDIYVHA
DLHGATSCVI KNPTGEPIPP RTLTEAGTMA LCYSAAWDAR VITSAWWVYH HQVSKTAPTG
EYLTTGSFMI RGKKNFLPPS HLMMGFSFLF KVDESCIWRH RGERKVRVQD EDMETLAICT
SELISEEMEQ LDGGDSSSEE DKEELHETPV EVELVTQVDQ GDITIQSGGD ELNELIQEES
SEDEGESEEV VKHQEPVGEM KDEGEETLHY PDTSVDLSHL QSQRSLQKLA SKEESSNMSD
SKLQSRRHLS AKERREMKKK KLPSDSGDLE MIEGKDKEKE NVLHIETHQN TSKNVPAVQP
MKRGQKSKMK KMKEKYKDQD EEERELIMKL LGSAGSNKEE KGKKGKKGKI KDEPVKKQPQ
KPKGGPRVSD SIKKETPSLE VTTHELQDLA VDDPHDDKEN LFDSLTGQPH PEDVLLFAIP
ICAPYNTMTN YKYKVKLTPG IQKKGKAAKT ALNSFMHSKE ATAREKDLFR SVKDTDLSRN
IPGKVKVSAP NLLNVKRK
//
