ID   A0A646KQ41_STRJU        Unreviewed;       286 AA.
AC   A0A646KQ41;
DT   22-APR-2020, integrated into UniProtKB/TrEMBL.
DT   22-APR-2020, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Tyrosinase family protein {ECO:0000313|EMBL:MQT04439.1};
GN   ORFNames=FF041_31075 {ECO:0000313|EMBL:MQT04439.1};
OS   Streptomyces jumonjinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1945 {ECO:0000313|EMBL:MQT04439.1, ECO:0000313|Proteomes:UP000419138};
RN   [1] {ECO:0000313|EMBL:MQT04439.1, ECO:0000313|Proteomes:UP000419138}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 5741 {ECO:0000313|EMBL:MQT04439.1,
RC   ECO:0000313|Proteomes:UP000419138};
RA   Moore M.A., Cruz-Morales P., Barona Gomez F., Kapil T.;
RT   "Comparative genomics and metabolomics analyses of clavulanic acid
RT   producing Streptomyces species provides insight into specialized metabolism
RT   and evolution of beta-lactam biosynthetic gene clusters.";
RL   Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:MQT04439.1}.
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DR   EMBL; VCLA01000192; MQT04439.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A646KQ41; -.
DR   Proteomes; UP000419138; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000419138}.
FT   DOMAIN          54..71
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          217..228
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   286 AA;  33045 MW;  AB0B565AD97E3479 CRC64;
     MYTRKNQRNL TPAEKRRLVD ALLTLKRSGH YDEFVRMHHA FYVPDGDSRP RPAHMTPSFF
     PWHRRYLLEF ESALQRIDPG VSIPYWDWTA DDTPAASLWA DDFMGGTGRV GDRQVMTGPF
     AYRNGNWRID SRLTDGRYLT RNLGRPSAPV SLPTADEVAE ALSEPWYDMA PWDSTSRGGF
     RNAIEGWSAS GAERWRNHNR VHRWVGGLML GSTSPNDPVF WLHHAFIDLL WVRWQRARPA
     AGYLPSDPLP PSDPQSGRIF ALHEPMPPWD EPPSLLLDHS RHYRYE
//