ID A0A653C0Z5_CALMS Unreviewed; 3720 AA.
AC A0A653C0Z5;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
GN ORFNames=CALMAC_LOCUS4866 {ECO:0000313|EMBL:VEN40837.1};
OS Callosobruchus maculatus (Southern cowpea weevil) (Pulse bruchid).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Chrysomeloidea; Chrysomelidae; Bruchinae; Bruchini; Callosobruchus.
OX NCBI_TaxID=64391 {ECO:0000313|EMBL:VEN40837.1, ECO:0000313|Proteomes:UP000410492};
RN [1] {ECO:0000313|EMBL:VEN40837.1, ECO:0000313|Proteomes:UP000410492}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sayadi A.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAACVG010006659; VEN40837.1; -; Genomic_DNA.
DR Proteomes; UP000410492; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13193; FERM_C_FARP1-like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR014847; FA.
DR InterPro; IPR041788; FARP1/FARP2/FRMD7_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45858:SF5; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 3.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000410492}.
FT DOMAIN 1..243
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1018..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1325..1357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1454..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1552..1710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1804..1829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1901..1931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2059..2139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2156..2181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2194..2228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2254..2312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2321..2340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2357..2421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2497..2584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2619..2720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2748..2881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2923..2944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3047..3214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..666
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1058
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1185..1199
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1326..1357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1482..1516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1552..1571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1575..1592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1597..1625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1658..1710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1805..1829
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2194..2211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2260..2310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2358..2387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2513..2544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2545..2572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2619..2642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2668..2717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2757..2773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2811..2825
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2847..2870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3073..3087
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3088..3103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3123..3184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3720 AA; 418261 MW; 18449208BCA21BA4 CRC64;
MHHSLSTPAV GDARPSGAGS PSSRKPGKML AVRVHMLDDN VTIFQVQAKA MGKVLFEQVC
KQLHLLEADY FGLEYSDAHG TKGLMQCNEN TAALMASYIV QAECGDYAAE DYPDHTYLST
YKFVPHQDHE LEKKIMENHK KHVRCELYGI KMHPAKDHEN VPLNLAVAHM GIIVFQNYTK
INTFSWAKIR KISFKRKRFL IKLHPEGYGY YKDTVEFFFE GRNECKNFWK KCVENHGFFR
CSSVKNVSRH KTRVLSRGSS FRYSGKTQKE IIEFVRDNYV KRQTFQSGSV QTVVGLPLFD
GGIGFGVSGR HSIGAQTTLS QCGFSDDEIS LSPPSAITAT AEPPAPEAAD TTTPPPQTTS
FSTRRIETGT TSTSTNAITR MPSNEGCPSQ TQSQSDLDRA ADYTYASLPK RHIWRRSASC
KDLYDFSFEE TGQAKRRLQP PRPMEKAVAS FEERKLESPV TQYDERPIYS ASSRDSSLEI
QQDIMVPDEK VYSSSYPGTT SFSVESVEDP GNYDLRDSQD DITHDSYELI EKSDDDYSTS
GEYQKYKVKP FNTRSCSLDS GNHIPSDSED EREKRHKCKS SSDVRQDIFL MDDPRDLPRE
IIPRKSDGSY YKQFKQSSRT SSLESKSDYY EPKPYRSSKE SLKKSHRDRS FGSRTSSLES
KSDYETKKTT KILSAEHLEA RNGYLDSRAS SLESKSEYYD APSKFVVDEP KYDFKHNYDR
KISFERNYGF HKVQNHDNAE INRNFTHVHS VSLQNVETEQ SLKINQLLAN IEQNTVPRTQ
KSHHYKPPTV NSRVWHDEIA AMAPEVPSWP QQQNTQRSTE SESNIFSFDD EKIQSLQESM
DSDVCPDHGF SVVPNLDNQN KKLDKRKNYR DVFMEIEPRL VHDLPLHQPI ERTKSDPNSL
ARQRLNSSSR RMLLMHQKSI DLTPAESSDE DYLYKQIPSA PPIMKYKGTQ FEMPSAEFGH
FDILKREVEG LKTKFEVPKS QFEILGAKTQ SDFINLPPKD EDISYVLHKR HILNGSAQKE
EIKQYEKPEP PKKSIIETKE TSKLDESKKS KPKEGKAGKA AETSFLFTQN IDLSKVDPVT
LEVDKTIAPV QHSLSPKRDI THIDPVLLET LSSKLSQIES DSPTSSKTES IKPQHKIFVM
QTERQVKKEV KTEEKAIQKP EEKKIPEVKP KTKIKTDIKP KRIIKPRMQP GKKSGKTTKT
KVRITSFSSD DESLDSDDVF GSAEAAPTRV EFSPPQMRKE MESILKFESE RKYLQYTMSS
TEVEGSPPTS RKKTEKPHES SFETVPTELR RISERSISIP SSEDEFNVKT TDLQPVFSEI
SQGALRTVDE LDKEDGDKSM DETLKEELPT EMELTAEDQE RLREKQLLQA EIEHDLRDLK
VPPKTKITEI PSPSLRKQGH SPLLFAHARL NLSEGSAFSL LQKQQALDSP IAGRRAKSLD
TPIIAVSRLP PLNAFSSKDD TVAEEDQQMT DKDSGLENNL ISDKSTEERS DTDMDERRRQ
YDLRESSSDM DRPPTEYKVA DSVTVTREIK MTKEQVSVTR EVKVTRQEIK VTEDSASKKK
EKERDQIVPD VNHVGSKKSK TTVHTKLYTQ KSKAKTPPKP PAKEKPATKT PAKAKVAEVK
KEIVPAKPVR PIPQKASSTE NASVKQSDMF LAAPEVKRTK SQEIETTNKK TPPKEKARSL
EKLELKRLGS KERSRSQEDS EPDIAKRKEK QQMLYEIAVQ STKTLKSPVK EILPVFPKVE
EMVRERGGKL EISINTIEPE VPLEDAIIIT KSPKKLDKKI GEKLTKSLDL TIPDDSSKAV
QRLGKSLDLD SRDKDEQSSG NEFDFKPETI KAMQDKEPIE ETSPEIDVVQ ETVTADIHQV
PPETETDDKI ILEGTSLDVW LSVDEPKETL DNIEVIQKST DFFEQGTSSK PPDLSKLDAK
SSSESQSLEK VSLGNSLDIR YIDSSTGDST YKSEKDAQLV AEMQKASSTV SKFLRKKLEK
RRQIEQHDSN LVKITSEEES LTEVSDLKGE IFEDRNFLSA TDAKDALLRL SIERSRSEDT
GSWITVDCEE FVGAEESLDY DNVTLESPDK PVETPIEQRS AEDINLLTTT ARHGKLEMLK
RSSDHSRSSD TTGSWTSGEK DLSPSGREVK ETDDSSASCA IGRAIGLSQT IEKFTTKDLL
DKGSPESDPQ RSPRSPRSPR ICILGRAFTI DEGNSVKLDN SSSSDETNDI PKDLTPIQEK
EGANGVGSYK KFPYPFEEKW SEDSELTKRL HKKLSKKLSS ADKGSLSSID DSFMDNQRNR
LKPTIEAFSS ESKTSVETTE SSSGSRSFKL NKQKHVIDRS ALERLSTDSR SLEDSSSGSK
SLRVHRVFDK NFDRLSTESR NSVDTTESSS GSLGQAYRTQ KSGDIPRELS STWKPFPLDS
SGSESFEDNL LPPDHEGDKQ EYFMCRDNSG EFTSMTDVYY KPDNDITPTR DDTVLPEDLA
NFNNFNYPCL PSIGIGGADI LGGYSGGAFL SRTLSRISER STNSEKSSVD DDSTKASTQS
DSLNDESLPS SNPQVSLSSE SPSHAHVSEH GKKTPTNLAE EEQDKVSDLS KPSGDRQDPM
PILGSLLQRQ ISDDRRTSAE MAELSIDDIE IISERGLKLK RQGSDDTIID EECFEPEPQQ
KEERIVTSSS QESEDWPLPE IPQGQKLLQM HETPSSDTSQ LTTQVYQPPN KNIPKTFGLR
GSSSIKSQES EQWPSPPSSI LEPVVGSVGT YYITPPEEAT KVIVESSTVS CEGESLSDEN
RTAELESSDK THIYENVPAD IPSESISESL SVGPSGVKIV LEEKPQDSNS DEELNISNLN
DDVFTESVEP SKHELRPPTA MRKSTASDDS SHSHHSDKKS SPKEGSHSSY SEEECTSSMG
TNLEDGTVRF ALKPTKCTHS SHSEDTSIAL SLSEWSNSTN TVKFQNLSSN SGTTKSSSGL
KSDENSLTDI AQSISEWSSS NASATIKTQQ QFQKFSSTTS TGESTLTELM PSISEWSSAE
TKPFFPAPQP NILGSSIDVE DFSLTQDQKG VPSPKNIPSE DLAMLTSSLP SRSEVKIHTR
STERPIVIPP PTLSDTDRSS SSMEQRTVHT QRYDKDKQKY LQKHQPPSKS LERPVKTPVK
LSKCPSYYSS SLSSESTPLA GTSPVPVTKP STVPVTRTHR KPISKSVSQA RSPTSENDST
SSVESPKSKS ERERRGYRRK RQIQNQRRAR LEKEQHTIEE TGPLEYSDFV RSRDMDEMAC
SFQYDNVLTE DIPIVHYSET LEEGYYPDGD SQSGSDIYRM EKEEEDKCEV VEGFDVASIP
PPLLEDDFED DVKQEMLDNS NGLNANVENN NFYCSTPIKP LNGNVYELSL KATNGTYTPP
RMDNEALKDY TKEQLMNSIN ANVTNSNINN TTTIIAEIEG EVKKKPRHFV DKTYYIAKEI
LMTELTYKKD LDVINVWFRS EVGKEQPEEC QILLSLIAPL AQAHGMLVKD LEQRLQGWDT
RGGPRADLML PVSETLEQSE NLATLCELQR DIIGFDSLVQ PGRKFIRHGC LLKHSRKGYQ
QRMFFLFSDI LLYTSRSQAT LQFKVHGHMP LRGVLIEEPD GDRQFNGLVI YGGSSDENVD
QVGNNNVGTQ TKPQAQRSNT TVHVCWHRST SISMKDTLLA VENQLSGYLL RKFKSSNGWQ
KLWVVFTSFC LFFYKGCLDE FPLASLPLLG YSVGPPAAED QIGKDFVFKL QYKNHGPLMI
//
