ID   A0A653DVJ0_CALMS        Unreviewed;       510 AA.
AC   A0A653DVJ0;
DT   22-APR-2020, integrated into UniProtKB/TrEMBL.
DT   22-APR-2020, sequence version 1.
DT   13-SEP-2023, entry version 13.
DE   RecName: Full=THAP-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CALMAC_LOCUS20495 {ECO:0000313|EMBL:VEN63770.1};
OS   Callosobruchus maculatus (Southern cowpea weevil) (Pulse bruchid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC   Chrysomeloidea; Chrysomelidae; Bruchinae; Bruchini; Callosobruchus.
OX   NCBI_TaxID=64391 {ECO:0000313|EMBL:VEN63770.1, ECO:0000313|Proteomes:UP000410492};
RN   [1] {ECO:0000313|EMBL:VEN63770.1, ECO:0000313|Proteomes:UP000410492}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sayadi A.;
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CAACVG010014840; VEN63770.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A653DVJ0; -.
DR   Proteomes; UP000410492; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 6.20.210.20; THAP domain; 1.
DR   InterPro; IPR006612; THAP_Znf.
DR   InterPro; IPR038441; THAP_Znf_sf.
DR   InterPro; IPR012934; Znf_AD.
DR   Pfam; PF05485; THAP; 1.
DR   Pfam; PF07776; zf-AD; 1.
DR   SMART; SM00980; THAP; 1.
DR   SMART; SM00868; zf-AD; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR   PROSITE; PS51915; ZAD; 1.
DR   PROSITE; PS50950; ZF_THAP; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00309};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000410492};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00309}.
FT   DOMAIN          1..84
FT                   /note="THAP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50950"
FT   DOMAIN          296..379
FT                   /note="ZAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51915"
FT   BINDING         298
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         301
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         352
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         355
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ   SEQUENCE   510 AA;  58027 MW;  B9C948C46F1A8DDE CRC64;
     MAMCFAPDCK HYSEKHVCRF FRFPKHPKDK KKWISLLRRK DREPSKHSVV CSCHFKDGDR
     KNGPTMFEHN KSKRFYDESC TSIGITKPKK LMKQLHETVV AEVASIEAEN YSLGKKLEKR
     EEELKKLYDS NIVSDQHKAK MIYPKRTDIS KISPVVVLKK NLQGSTAITD VPQAINVCQK
     GTELSKKCPI VVLERNVPDN TRISYISKVS TVGQERTDTS KMSAVVVHKK IVQDNVGSEI
     SNVSSVGQKG TDNSKIFPTV VLKKNFQDST STTDIPKVNI STKEKYFYHR KTDISNMCRA
     CLTQSPKTMY DLTDVIEVIT GSCSNKVSII EALQTVTSTT IVINPKYPQY ICPICLSMLK
     MAYRFILNFK ESQMQLEKTV GLVDDIDNEM TVTLNIEETE INTEQNKIEL LTDDNMDIEE
     CEIKCSPLSE FDSEITDSEA HGKLEVSTLD EDIDSDKHLE KEGKEVDDNW KSGKVELIIE
     EEEFDTSDIN DVEDEECVAE FDGSFIIRAR
//