ID A0A662XDT2_9STRA Unreviewed; 626 AA.
AC A0A662XDT2;
DT 22-APR-2020, integrated into UniProtKB/TrEMBL.
DT 22-APR-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN ORFNames=BBJ28_00009836 {ECO:0000313|EMBL:RLN74801.1};
OS Nothophytophthora sp. Chile5.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Nothophytophthora.
OX NCBI_TaxID=2483409 {ECO:0000313|EMBL:RLN74801.1, ECO:0000313|Proteomes:UP000274840};
RN [1] {ECO:0000313|EMBL:RLN74801.1, ECO:0000313|Proteomes:UP000274840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile5 {ECO:0000313|EMBL:RLN74801.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLN74801.1}.
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DR EMBL; MBAC02006323; RLN74801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A662XDT2; -.
DR Proteomes; UP000274840; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000274840};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..626
FT /note="Tyrosinase copper-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5024832245"
FT DOMAIN 75..92
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 243..254
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
FT REGION 362..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 66928 MW; 27685074C10B215C CRC64;
MKLVWALSIG LLALVSSLTP ADAQTCGTRV RRDWDALSTA DKTTYKGALA AAMDSGAYIK
FVEMHTEMMS EMEAHRQCMF IYWHRLLLVV FENMRGQGSA YACVTVPYFN WVGANNRVLT
GSCSSLGDCS AITKELGGYT VGSQTTLTIN GVTGNSGVCV TEAPLNHFCQ SGSVTGAACA
HCVPRGAWGS ASVPTTTSYA SIRQQVFNGK NIGEMSPLVE QGCHNNVHAN LAGTMGTFAS
PSDPIFWSHH AMVDALHTIF HKCRVGTQRM TFAQKAANPV AWTSCARRDG GVFDPTDVIT
MRTGVNGVNP IEGSQDPIIG QYFTGVPNQF AGLMDVRDLG DSSYSYELSG QLASMYNDCD
GTSTSAPTTT APTPTTTAPT PTTTAPTPTT TAPVPTTTTR APVSTTRTPV STTRAPVPTT
RAPVATAAPT PTSPSRRGWS WLNWLRNHGH SRNLEAEHGH HKSNNCADTS DQQTGVSTSA
PTIDPSTMYQ DDHVDVIIVD DCSVSEQRVS SWYDESLSAM GGQCPENMAD LERQACMYEN
QCLGGTADYS DEFKAVWGAV EPRCLTIVNA INSGEQSILY ESWRETMEAH FGCPTPANAT
TVDQNTGYGG VTDVIANTTS DAVQSV
//
