ID A0A663EKE9_AQUCH Unreviewed; 581 AA.
AC A0A663EKE9;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Dynein cytoplasmic 1 intermediate chain 2 {ECO:0000313|Ensembl:ENSACCP00020012812.1};
GN Name=DYNC1I2 {ECO:0000313|Ensembl:ENSACCP00020012812.1};
OS Aquila chrysaetos chrysaetos.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Aquila.
OX NCBI_TaxID=223781 {ECO:0000313|Ensembl:ENSACCP00020012812.1, ECO:0000313|Proteomes:UP000472275};
RN [1] {ECO:0000313|Ensembl:ENSACCP00020012812.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00011059}.
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DR AlphaFoldDB; A0A663EKE9; -.
DR Ensembl; ENSACCT00020013398.1; ENSACCP00020012812.1; ENSACCG00020008735.1.
DR GeneTree; ENSGT00940000155442; -.
DR Proteomes; UP000472275; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12442:SF37; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2; 1.
DR PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR Pfam; PF11540; Dynein_IC2; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000472275};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 415..462
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 27..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 64558 MW; 26BBEEDCD427F534 CRC64;
AKQLHETVQP LRVVTADTCL FHYLVPPPTS PSSKSVSTPS EAGSQDSGDG AVGSRTLHWD
TDPSVLQLHS DSDLGRGPVK LGMAKITQVD FPPREIVTYT KETQTPVMTQ PKEDEEDEDD
VVAPKPLAEP EEEKTLKKEE EEEGTAAPHE LTEEEKQQIL HSEEFLSFFD HSTRIVERAL
SEQINIFFDY SGRDLEDKEG EIQAGAKLSL NRQFFDERWS KHRVVSCLDW SSQYPELLVA
SYNNNEDAPH EPDGVALVWN MKYKKTTPEY VFHCQSAVMS ATFAKFHPNL VVGGTYSGQI
VLWDNRSNKR TPVQRTPLSA AAHTHPVYCV NVVGTQNAHN LISISTDGKI CSWSLDMLSQ
PQDSMELVHK QSKAVAVTCM SFPIGDVNNF VVGSEEGSVY TACRHGSKAG ISEMFEGHQG
PITGINCHAA VGPVDFSHLF VTSSFDWTVK LWTTKNNKPL YSFEDNSDYV YDVMWSPTHP
ALFACVDGMG RLDLWNLNND TEVPTASITV EGNPALNRVR WTHSGREIAV GDSEGQIVIY
DVGEQVSVPR SDEWTRFGRT LAEINANRAD AEEEAATRIP A
//
