ID A0A663EN55_AQUCH Unreviewed; 451 AA.
AC A0A663EN55;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Serine incorporator 2 {ECO:0000313|Ensembl:ENSACCP00020013697.1};
GN Name=SERINC2 {ECO:0000313|Ensembl:ENSACCP00020013697.1};
OS Aquila chrysaetos chrysaetos.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Aquila.
OX NCBI_TaxID=223781 {ECO:0000313|Ensembl:ENSACCP00020013697.1, ECO:0000313|Proteomes:UP000472275};
RN [1] {ECO:0000313|Ensembl:ENSACCP00020013697.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TDE1 family.
CC {ECO:0000256|ARBA:ARBA00006665}.
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DR AlphaFoldDB; A0A663EN55; -.
DR Ensembl; ENSACCT00020014317.1; ENSACCP00020013697.1; ENSACCG00020009449.1.
DR GeneTree; ENSGT01030000234623; -.
DR InParanoid; A0A663EN55; -.
DR OrthoDB; 53161at2759; -.
DR Proteomes; UP000472275; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005016; TDE1/TMS.
DR PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR PANTHER; PTHR10383:SF22; SERINE INCORPORATOR 2; 1.
DR Pfam; PF03348; Serinc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000472275};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..451
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025621982"
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 451 AA; 49364 MW; 81C6DB7B06C31DEA CRC64;
MGACLGVCSL LSCVSCLCGS APCLLCGCCP SAKNSTVSRL LFTFFLFLGT LVSIIMIIPG
VEKELHKLPG FCEGSGSVLG VQTHVDCSSF LGHKAVYRMG FAMAAFFFLF ALLMVCVRSS
KDPRAAVQNG FWFFKFLVLV GITVGAFYIP DGAFTSVWFY FGVVGSFLFI LIQLVLLIDF
AHSWSQLWLH NAGESNAKGW YAALCIITFI FYATSIAAIV LLYIYYTKPE GCTEGKVLIS
INLILCLIIS AVSILPKIQD AQPHSGLLQA SLITLYTIYV TWSALANVPT QTCNPTLLVR
NSTGSATATQ PLTTWWDAPS IVGLIIFILC TLFISVRSSD HPQVNKLMLT EESAAGAGGE
AAAVESGLHR AYDNEQDGVS YNYTFFHLCL LLAALYIMMT LTNWYRPDES LRVLTSPWTA
VWVKICSSWA GLLLYLWTLV APLVLPNRDF S
//
