ID A0A665WMB4_ECHNA Unreviewed; 629 AA.
AC A0A665WMB4;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSENLP00000044885.1};
GN Name=LOC115058914 {ECO:0000313|Ensembl:ENSENLP00000044885.1};
OS Echeneis naucrates (Live sharksucker).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Echeneidae; Echeneis.
OX NCBI_TaxID=173247 {ECO:0000313|Ensembl:ENSENLP00000044885.1, ECO:0000313|Proteomes:UP000472264};
RN [1] {ECO:0000313|Ensembl:ENSENLP00000044885.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR AlphaFoldDB; A0A665WMB4; -.
DR Ensembl; ENSENLT00000045997.1; ENSENLP00000044885.1; ENSENLG00000019097.1.
DR Proteomes; UP000472264; Unplaced.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221:SF22; TAF6-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L; 1.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472264};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..73
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 461..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 68702 MW; FA3E416BF2570530 CRC64;
MADREERRFA EISRESVKFM AESTGVELGD DVAGLLAEDV CYRLREATQS SSQFMRHAKR
RKLTVEDFNR ALHWSNVEAI CGYGAQDTLP FRSAKEGELF FIEDRDINLV ELALATNIPK
GCAETMVRVN VSYMDGKGNL EPQGTVPSAV QSLSDDLLKY YQQITRAILG EDPHLMKVAL
LDLQSNAKIA ALLPYFVYVI SGVKSVSHDL EQLNRLLHMV KSLVQNPYLY LGSYIRSLVS
SVMYCILEPL AASINPLNDH WTLRDYAALL LSHIFWTHGD LVSGLYHQIL VSLQKVLSDP
VRPLCSHYGA VVGLHALGWK AVERVLFPHL PAYWANLQAV LDDYSVSNAQ VKADGHKVYG
AILVAVERLL KMKALSLSQQ SDGGSSGQTG FAGGSICYRV SSPGLSPPPE PLSEATLGIA
SHLQAGGAGC PLEEWTPVPL PAMYCELYSF FGDSLAVRFS TGPGDARKEP PGPTSNPDTT
RKMPQLTANL NISPRHDGSP RTDPTPPSLA ATGSGRSLTR SCSSSSSVQR SRSSSRSGQR
SAGLSRDVFP KARFTSSQTG PPAFSFLIGG RQMGLRCQGR RPFQTNFAPT PPLSAVPPRA
YAHKLPVIGR VGKPVRRWAC SHYSLHLPL
//
