ID   A0A667WZ60_9TELE        Unreviewed;       621 AA.
AC   A0A667WZ60;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=T-box transcription factor 21 {ECO:0000313|Ensembl:ENSMMDP00005010810.1};
GN   Name=tbx21 {ECO:0000313|Ensembl:ENSMMDP00005010810.1};
OS   Myripristis murdjan (pinecone soldierfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Holocentriformes; Holocentridae; Myripristis.
OX   NCBI_TaxID=586833 {ECO:0000313|Ensembl:ENSMMDP00005010810.1, ECO:0000313|Proteomes:UP000472263};
RN   [1] {ECO:0000313|Ensembl:ENSMMDP00005010810.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00201}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR   AlphaFoldDB; A0A667WZ60; -.
DR   Ensembl; ENSMMDT00005011139.1; ENSMMDP00005010810.1; ENSMMDG00005005843.1.
DR   GeneTree; ENSGT00940000166447; -.
DR   InParanoid; A0A667WZ60; -.
DR   OrthoDB; 5323209at2759; -.
DR   Proteomes; UP000472263; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IEA:UniProt.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd20203; T-box_TBX21; 1.
DR   Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032385; T-box_assoc.
DR   InterPro; IPR046360; T-box_DNA-bd.
DR   InterPro; IPR036960; T-box_sf.
DR   InterPro; IPR001699; TF_T-box.
DR   InterPro; IPR018186; TF_T-box_CS.
DR   PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11267:SF125; T-BOX TRANSCRIPTION FACTOR TBX21; 1.
DR   Pfam; PF00907; T-box; 1.
DR   Pfam; PF16176; T-box_assoc; 1.
DR   PRINTS; PR00937; TBOX.
DR   SMART; SM00425; TBOX; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS01283; TBOX_1; 1.
DR   PROSITE; PS01264; TBOX_2; 1.
DR   PROSITE; PS50252; TBOX_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00201};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000472263};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          160..345
FT                   /note="T-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50252"
FT   REGION          350..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          392..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          479..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          505..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..420
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        479..496
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..526
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        585..604
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   621 AA;  68202 MW;  943AE5DE2EF2A702 CRC64;
     MGGIGGNLYL SMLNGTETQT FGKDGDISNH LHRGGKDLAE FKMGIQDARF YYPDTVQSGQ
     DALALPYHSD QTVGGYGAQP GRFYAQSLSS CPYGGVRSPT RSAAGQGYIP AAGDGFSTGG
     KEVYPASPEN YPATFQHGYQ RPPLYPIPGL QVCGKTQALL NNYPLWAKFH KFQTEMIITK
     QGRRMFPFLS FNISVLDPSA HYNVYVDVVL ADQHHWRYQG GKWVQCGKAE GNMPGNRMYM
     HPDSPNTGAH WMRQEVSFGK LKLTNNKGST NNVAQMIVLQ SLHKYQPRLH IVEVKEDGTE
     DPFLSAKAQT FVFPETQFIA VTAYQNADIT QLKIDHNPFA KGFRDNYDTL YAPPDSDRLT
     PSPTESQQLL PGTCYPQGYL SEQYMSPLPQ SRFYGREPIS MGQQPKDPSS SPSPHSRWYL
     SPQQNVASNR LDFASSYDGD FSSNSFYKPF PLQTSAHHAL GYYADHPFAS ASMSVSGASS
     AGWSTSRPSP QYLSHASKPG PSLGWFRPVS SSSSSSSSST SPGNPRLHPP SLLEPLRPAL
     LQDKPKDTSG VIGEDPWLEP PSVKSVDSAD SGLFEGGAGE SKKRRVSPYT SSTENSPPTR
     SVEICEKDSN SDAGYYGFYT H
//