ID A0A669AYZ3_ORENI Unreviewed; 842 AA.
AC A0A669AYZ3;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Band 4.1-like protein 1 {ECO:0000313|Ensembl:ENSONIP00000028641.1};
GN Name=LOC100695288 {ECO:0000313|Ensembl:ENSONIP00000028641.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000028641.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000028641.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A669AYZ3; -.
DR Ensembl; ENSONIT00000072783.1; ENSONIP00000028641.1; ENSONIG00000020256.2.
DR GeneTree; ENSGT00940000158442; -.
DR Proteomes; UP000005207; Linkage group LG5.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF24; BAND 4.1-LIKE PROTEIN 1; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 51..332
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 95344 MW; 404E98FCF813D22F CRC64;
MQDSASDSKI AKQEQNKHMD GHRETDDMSE KTSPNKNLKS PQKGSKRLKT APFKVTLLDS
SEFEGETEKH SKGQTLMDMV CEHLNLLEKD YFGLTFADTD SQKNWLDPSK EIKKQMRNSP
WHFAFAVKFY PPDPSQLMED ITRYYLCLQL RDDMLSGRLP CSFVTHALLG SYTVQAELGD
YDQDDHGTDY VSDFRFAPNQ TRELEERVME LHRNYKGMTP AEAEMNFLEN AKKLSMYGVD
LHHAKDSEGI EIMLGVCANG LLIYRDRLRI NRFAWPKILK ISYKRSNFYI KIRPGEYEQF
ESTIGFKLPN HRAAKRLWKV CIEHHTFFRL VSPEPPPKGF LVMGSKFRYS GRTQAQTRQA
SALIDRPAPH FERSTSKRYL LSRSLDGEFS RPVSAMCENH DGLSHRSISE HRRLHSPSGD
EQETELEPSL EQDEEEKEHE QGREAEQDKD HDGNVTPSRK KEIMFLDKSQ DVLLKHQASI
NELKRALREP NSKLMNREKR LSATSPTGTP EKKALVGRAM GKEPVNSLSV EGFVQKTLVT
SPEEPVSTPA IYEEPFADFK KEFGERRPQP SIASEEEQER DTVACMKETH LGIERKCSSM
TVSSTSSLEA EVDFTVITDL HSGLEDFSKG VPELGERERQ PEVGREDFEE TSRFYSARLM
GSRDKSPIEE RLPEEGMHHE PPVAKKDPNA VSVAHKLKRA DSKTETHTNG SEAHANVVNV
SPENYGVVSP QEAPAAVKEN GSPVKASTQG RESVVSPLTI TAESVTSATT TQVTKTVKGG
YSETRIEKRI IITGDDDVDQ HQALAMAIQE AKQQHPDMLV TKAVVIRETE SPTEELQQKA
ES
//
