ID A0A669BSW9_ORENI Unreviewed; 426 AA.
AC A0A669BSW9;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Gap junction Cx32.2 protein-like {ECO:0000313|Ensembl:ENSONIP00000038453.1};
GN Name=LOC102079568 {ECO:0000313|Ensembl:ENSONIP00000038453.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000038453.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000038453.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR Ensembl; ENSONIT00000048678.1; ENSONIP00000030358.1; ENSONIG00000015241.2.
DR Ensembl; ENSONIT00000068326.1; ENSONIP00000038453.1; ENSONIG00000015241.2.
DR GeneTree; ENSGT01090000260005; -.
DR Proteomes; UP000005207; Linkage group LG23.
DR GO; GO:0005922; C:connexin complex; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 1.20.1440.80; Gap junction channel protein cysteine-rich domain; 2.
DR InterPro; IPR000500; Connexin.
DR InterPro; IPR019570; Connexin_CCC.
DR InterPro; IPR013092; Connexin_N.
DR InterPro; IPR038359; Connexin_N_sf.
DR PANTHER; PTHR11984; CONNEXIN; 1.
DR PANTHER; PTHR11984:SF53; GAP JUNCTION PROTEIN; 1.
DR Pfam; PF00029; Connexin; 2.
DR PRINTS; PR00206; CONNEXIN.
DR SMART; SM00037; CNX; 2.
DR SMART; SM01089; Connexin_CCC; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..78
FT /note="Connexin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00037"
FT DOMAIN 133..199
FT /note="Gap junction protein cysteine-rich"
FT /evidence="ECO:0000259|SMART:SM01089"
FT DOMAIN 260..293
FT /note="Connexin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00037"
FT DOMAIN 347..413
FT /note="Gap junction protein cysteine-rich"
FT /evidence="ECO:0000259|SMART:SM01089"
SQ SEQUENCE 426 AA; 47760 MW; F35A1FBC24CF0C80 CRC64;
MTNQKLGFLS SVLCKWHAQA TLIGKYLLPV LLLIRFVMLG AAVQTAWLND REEFLCSTQQ
PGCETACFDA VTPLSLPRLW TLQLVLVLAP GLVFLCYLIH LTNQETQVQR GNDEVKGHTL
SVYRACVAFV IVVEVGCIAA QWLLYGFELS TDFSCGRSPC PMRVDCFLPH AWEKTVFLRI
MFTASSVSIL LNVVEAVCML RAKLRRTDGG ETLQSGSQVE ESVLSRLLAL WHSHAGFLGK
TVLPVLQLVR IVLVGAAVQP LWSHDLKYFV CDTDQPACSR EAYNFAFPFS WHQYWTLQVV
FVLAPGLIYF SYLVHLLVTQ KQSETGTVIK RQSLWAYLGF LSAVVLLEVG FAVGQCLKFG
LFLPPMFNVA VSPCPHTVDC FLPQPNEKSV FMFIMLVLAC LSGLLTLVEM VSSQFEWWFM
LMGIFS
//
