ID   A0A669C1A4_ORENI        Unreviewed;       840 AA.
AC   A0A669C1A4;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Intraflagellar transport 88 homolog {ECO:0000313|Ensembl:ENSONIP00000041602.1};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000041602.1, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000041602.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A669C1A4; -.
DR   Ensembl; ENSONIT00000056848.1; ENSONIP00000041602.1; ENSONIG00000015723.2.
DR   GeneTree; ENSGT00390000015473; -.
DR   InParanoid; A0A669C1A4; -.
DR   OMA; RIKIMHN; -.
DR   Proteomes; UP000005207; Unplaced.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR44117; INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG; 1.
DR   PANTHER; PTHR44117:SF1; INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   Pfam; PF13174; TPR_6; 2.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00028; TPR; 11.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 7.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          231..264
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          270..303
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          483..516
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          517..550
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          551..584
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          585..618
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          619..652
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          41..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          110..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          723..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        723..742
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        745..778
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  95097 MW;  F403197EED0BFBEF CRC64;
     MEHVHLAVEE DDLYSGYNDY NPTFDSEELE NDVGFQQAVR TSHGRRPPMT AKFPGTPIGP
     RSLATSFGAR LHMASSMGRP MTGAVQDGSA RPMTAVRAAG YTSALSRGSA FDPLGQSRGP
     APALEAKNED TPEEKIKILE KKVNDLIEES CMAQSMGALQ VALEKAKEAG RKERALVRQR
     EQSGSADHIN LDLTYSVLLN LANQYTNNEM YPEALNSYQI IVKNKMFSNA GRLKVNMANI
     YFKQKNYPKA IKFYRMALDQ ITNAHKEMRI KIMQNIGVVF ICMGQYTDAI TSFEHIMSES
     PNIKTGFNLI LCYYAIGDRE RMKKAFQKLI SVPLGIDDED KYIPSNEDTS SNMVIEAIKN
     DKLHQMERDL KTLAEKYIMT AAKLIAPAIE TLFATGFDWC VDMVKSSQYV ELANDLEINK
     AITYLRQKDF NQAVETLKAF EKKDSRVKSA AATNLSFLYF LEKDYDQADR YADLAMNADR
     YNPAALINKG NTVFVKQEYE KAAEFYKEAL RNDSSCTEGL YNLGLTYKRL NRLEEALDCF
     LKLHAILRNS SQVMYQLASL YELLENPEQA IEWLMQVISV TPTDAQALAK LGELHDGEGD
     KSQAFQYYYE SFRYFPSNID VIEWLGAYYI ETQFCEKAIQ YFERATLIQP TQVKWQLMVA
     SCYRRSGNSQ KALETYKEIH RKFPENVECL RFLVRLCTDM QLKEVQDYAT KLKKVEKMKE
     IREQRIKSGR EGSARSRREG RESSAGSAGI STPVLISPKK SSVMDSGRSS SSTKGERLSA
     KMRSLPGSNE PYEASSPKEL DASYVDPLGP QMDRPKTGVK KRVEDDDFAD EELGDDLLPE
//