ID A0A669CID6_ORENI Unreviewed; 497 AA.
AC A0A669CID6;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Desmin b {ECO:0000313|Ensembl:ENSONIP00000047129.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000047129.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000047129.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A669CID6; -.
DR Ensembl; ENSONIT00000060648.1; ENSONIP00000047129.1; ENSONIG00000012177.2.
DR GeneTree; ENSGT00940000155522; -.
DR InParanoid; A0A669CID6; -.
DR OMA; AWMCCLW; -.
DR Proteomes; UP000005207; Linkage group LG23.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF19; ZGC:154009; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..497
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025647432"
FT DOMAIN 131..439
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 135..290
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 323..417
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 497 AA; 56515 MW; 2939E2B9B93E3619 CRC64;
MRAAGSSSVI LSAAALASLS VSSNMASYSS SGQTASSYRR TFGHGTYASP SLNRSLLGHS
GSGGGHVSSR VYEVTRTSAT PAYRVSSSYY GRPATTSRAS VGRSYAGMGE TLDFSLADAL
NQEFLTTRTN EKAELQHLND RFASYIEKVR FLEQQNQALV VEVERLRGRE PTRIADLYEE
EMSELRRQVE ILTNQRSRIE VERDNLLDDL DKLKIRLQEE ILQKEEAENN LAAFRADVDA
ATLARLDLER RIETLQEEIA FLKKIHEEEI RELQAQMQET QVQIQMDMSK PDLTAALRDI
RAQYEGIAAK NIAEAEEWYK SKVSDLNQAV SKNNEALKQA RQETMEFRHQ IQAYTCEIDS
LKGTNESLMR QMRDMEDRHG REAGTYQDNI ARLEAEIANM KDEMARHLRE YQDLLNVKMA
LDVEIATYRK LLEGEESRIA LPVQTYSTLS FRETSPEQQR SSEMHSKKTV LIKTIETRDG
EVKLLRYKTA FISLVSF
//
