ID A0A669D049_ORENI Unreviewed; 683 AA.
AC A0A669D049;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Metastasis associated 1 {ECO:0000313|Ensembl:ENSONIP00000053958.1};
GN Name=MTA1 {ECO:0000313|Ensembl:ENSONIP00000053958.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000053958.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000053958.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A669D049; -.
DR Ensembl; ENSONIT00000046750.1; ENSONIP00000053958.1; ENSONIG00000000969.2.
DR GeneTree; ENSGT01030000234573; -.
DR Proteomes; UP000005207; Linkage group LG19.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF5; METASTASIS-ASSOCIATED PROTEIN MTA1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..81
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 82..193
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 200..252
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 468..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 77349 MW; 933FB8DB09F3CD67 CRC64;
YTEQISGRMR DLPEKQKHQL RHRELFLSRQ LESLPATHIR GKCCVTLLNE TEALKSYLDR
EDAFFYSLVY DPQQKTLLAD KGEIRVGNKY QADITDLLKE GEDDGRDLEK MEEKIWDSNS
SLTEKQIDQF LVVARSVGTF ARALDCSSSV RQPSLHMSAA AASRDITLFH AMDTLHATGY
DMTRAIAALV PQGGPVLCRD EMEEWSASEA NLFEEALEKY GKDFTDIQQD FLPWKSLTSI
IEYYYMWKTT DRYVQQKRLK AAEAESKLKQ VYIPNYNKPN PNQLSNNVKP ALVNGAAGTA
GTVGTAGTAV PGPPGSVPTP GLGRACESCY TSSSYQWYSW GPPNMQCRLC ASCWTYWKKY
GGLKMPTRLD GERPGPNRNN MVQSPHGLPL RHSGSPKFAV KTRQAFYLQT TSLTRMARRI
CQDIIRPRYM ARHPYLPVNT AAIKAESRYY DKMNLFPLSF SSCVSDHVSE AHPRPSKPNP
PTRGGSISTG SLTPIKSSPI LNNGSPTILG KRTYEQHNGL DGEPDRLETL KHIYNLRVFA
SSASKNFIFT ELLFVTTTIE DYFHLQWYIF GSMSLFLHLS TLPHRYVENQ RRGEQQQHQG
FCIEQSRLGW GWVAMWLADV QYLWAGRNIS AFKSVSLNSA HAQVMLDMLN ISSIGFFRLV
IFWLLKTCTI NMHSNQNPLC GSK
//
