ID   A0A669DDG0_ORENI        Unreviewed;       334 AA.
AC   A0A669DDG0;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Protein prune homolog 2 {ECO:0000256|ARBA:ARBA00039860};
DE   AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1 {ECO:0000256|ARBA:ARBA00042084};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000058664.1, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Proteomes:UP000005207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Broad Institute Genome Assembly Team;
RG   Broad Institute Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSONIP00000058664.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A669DDG0; -.
DR   Ensembl; ENSONIT00000073861.1; ENSONIP00000058664.1; ENSONIG00000027318.1.
DR   GeneTree; ENSGT00940000154422; -.
DR   InParanoid; A0A669DDG0; -.
DR   OMA; FNKHGDS; -.
DR   Proteomes; UP000005207; Linkage group LG12.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   PANTHER; PTHR12112; BNIP - RELATED; 1.
DR   PANTHER; PTHR12112:SF11; PROTEIN PRUNE HOMOLOG 2; 1.
DR   Pfam; PF12496; BNIP2; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   4: Predicted;
KW   Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          133..287
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000259|PROSITE:PS50191"
FT   REGION          18..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..83
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  38244 MW;  FD3FF91F485F2329 CRC64;
     MTTFNNLTPI ALPSIRPWFS PSSADISGGS NQRRKLAAPP MNVSLDHSEG SLLSEDTLDT
     EDDGLDTGDD LDVNLDELDT PDEADSLEFN KHGDSEESVL GAGAASRDPG HRAAEESRLW
     RSVVIGEQEH RIDMKCIEPY KRVISHGGYY AEQKAIIVFA ACFLPESNCD NYNYVMENLF
     LYVISTLELM VAEDYIIVYL NGATPRRRMP GFTWMKRCYQ MIDRRLKKNL KMFIIVHPSW
     FIRTLLGITR PFIRSQSFKV MEISIRKYVH SLQELGEIIP MEYVHIPHSI TIKLCPKNGC
     EPAHKTNLVQ PIGYTRKCET CKEKWQKLQM FQKF
//