ID   A0A669ES76_ORENI        Unreviewed;       437 AA.
AC   A0A669ES76;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Ganglioside induced differentiation associated protein 2 {ECO:0000313|Ensembl:ENSONIP00000074215.1};
GN   Name=gdap2 {ECO:0000313|Ensembl:ENSONIP00000074215.1};
OS   Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX   NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000074215.1, ECO:0000313|Proteomes:UP000005207};
RN   [1] {ECO:0000313|Ensembl:ENSONIP00000074215.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDAP2 family.
CC       {ECO:0000256|ARBA:ARBA00008355}.
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DR   AlphaFoldDB; A0A669ES76; -.
DR   Ensembl; ENSONIT00000057395.1; ENSONIP00000074215.1; ENSONIG00000015675.2.
DR   GeneTree; ENSGT00940000156336; -.
DR   Proteomes; UP000005207; Unplaced.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR   PANTHER; PTHR11106:SF72; GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF52949; Macro domain-like; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT   DOMAIN          1..176
FT                   /note="Macro"
FT                   /evidence="ECO:0000259|PROSITE:PS51154"
SQ   SEQUENCE   437 AA;  49446 MW;  FFD4DE2CF3ADF9DA CRC64;
     MIIIGDTVIP QCVGDIALLN CTAVVNTSNE SLNDKNPTSD SIHQLAGPEL RDELLKLKGC
     RTGEAKLTKG FNLAARFIIH TVGPKYKAKY RTAAESSLYS CYRNIMQLAA EQSMASVGFC
     VVTTTKRGYP LEDATHIALR TVRRFLENHG NSIETVVFAV SDIEESAFKK LLPLYYPRSE
     GEEKTCLPLI PADIGNSEGE PVVPERQIRI TEKPGSIEDE CDEDSLELDL GQVGTHAFAR
     MEGDVDKQRK LILQGQMSEA ALQKQHQRNY GRWLCRARAE DLSDIAALKA LYQTGVDVCG
     RTVMVVVGRN IPVTLIDLEK ALLYFIHVMD HITVKEYVMV YFHTLTGEHN HLDTDFLKKL
     YDIVDVKYKK NLMAFYFVHP TFRSKVSTWF FTTFSVSGMK EKVRYLDNLQ QLFTCIKPEQ
     IDIPPFVLEY DARVRTQ
//