ID A0A669EXI3_ORENI Unreviewed; 631 AA.
AC A0A669EXI3;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Phosphatidylinositol-binding clathrin assembly protein {ECO:0000313|Ensembl:ENSONIP00000075617.1};
GN Name=LOC100697286 {ECO:0000313|Ensembl:ENSONIP00000075617.1};
OS Oreochromis niloticus (Nile tilapia) (Tilapia nilotica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Oreochromini; Oreochromis.
OX NCBI_TaxID=8128 {ECO:0000313|Ensembl:ENSONIP00000075617.1, ECO:0000313|Proteomes:UP000005207};
RN [1] {ECO:0000313|Proteomes:UP000005207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Broad Institute Genome Assembly Team;
RG Broad Institute Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Oreochromis niloticus (Nile Tilapia).";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSONIP00000075617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PICALM/SNAP91 family.
CC {ECO:0000256|ARBA:ARBA00008011}.
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DR AlphaFoldDB; A0A669EXI3; -.
DR Ensembl; ENSONIT00000038094.1; ENSONIP00000075617.1; ENSONIG00000011152.2.
DR GeneTree; ENSGT00950000183068; -.
DR Proteomes; UP000005207; Linkage group LG14.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:InterPro.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR CDD; cd16985; ANTH_N_AP180; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF89; PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005207}.
FT DOMAIN 14..145
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT COILED 325..352
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 631 AA; 68812 MW; EC96592DD092BB79 CRC64;
MSGQSITDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIHCTN EMNVNIPQLA
DSLFERTTNT SWVVVFKSLI TTHHLMVYGN ERFVQYLASR NTLFNLSNFL DKSGLQGYDM
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GVDGVMRTMN TEKLLKTIPI IQNQMDALLD
FNVNANELTN GVINAAFMLL FKDSIRLFAA YNEGIINLLE KYFDMKKTQC KEGLDIYKKF
LTRMTRISEF LKVAEQVGID RGDIPDLSQF TVCAPSSLLE ALEQHLASLE GKKVKDSTAA
SRASTLSNAV SSLASTGMSF TKVDEREKQA ALEEEQARLK ALKEQRLKEL SKRPSFATTD
TSPISTTGGT ISTAPAIDLF STPSCSNGAV KMESDLFDLQ PTFQPSMQSG TTGLPAATAW
ADSFCGPVSI AQHLPHQAPF PTEPSSVAGL FRGYSTPQAP PQPTAGGLQV DFESVFGAKA
AGSSSLNSDD ITGGILKPTL AGSNQPSNQQ PEKLVSDDLD SSLANLVGNL GIGNGTMKND
IHWSQPGEKR MTGGTNWQPK AAPTTTWNPV SMPPSIMAFP ATTPTGMMGY GMPQQMGSMG
MMNPPTMMYS QPVMRPPNPF SSVSSAQMQF M
//
