ID   A0A670I594_PODMU        Unreviewed;       193 AA.
AC   A0A670I594;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=P53 apoptosis effector related to PMP-22-like {ECO:0000313|Ensembl:ENSPMRP00000006885.1};
GN   Name=LOC114594182 {ECO:0000313|Ensembl:ENSPMRP00000006885.1};
OS   Podarcis muralis (Wall lizard) (Lacerta muralis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata;
OC   Lacertibaenia; Lacertidae; Podarcis.
OX   NCBI_TaxID=64176 {ECO:0000313|Ensembl:ENSPMRP00000006885.1, ECO:0000313|Proteomes:UP000472272};
RN   [1] {ECO:0000313|Ensembl:ENSPMRP00000006885.1, ECO:0000313|Proteomes:UP000472272}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=30819892; DOI=10.1073/pnas.1820320116;
RA   Andrade P., Pinho C., Perez I de Lanuza G., Afonso S., Brejcha J.,
RA   Rubin C.J., Wallerman O., Pereira P., Sabatino S.J., Bellati A.,
RA   Pellitteri-Rosa D., Bosakova Z., Bunikis I., Carretero M.A., Feiner N.,
RA   Marsik P., Pauperio F., Salvi D., Soler L., While G.M., Uller T., Font E.,
RA   Andersson L., Carneiro M.;
RT   "Regulatory changes in pterin and carotenoid genes underlie balanced color
RT   polymorphisms in the wall lizard.";
RL   Proc. Natl. Acad. Sci. U.S.A. 116:5633-5642(2019).
RN   [2] {ECO:0000313|Ensembl:ENSPMRP00000006885.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM47 family.
CC       {ECO:0000256|ARBA:ARBA00008691}.
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DR   AlphaFoldDB; A0A670I594; -.
DR   Ensembl; ENSPMRT00000007358.1; ENSPMRP00000006885.1; ENSPMRG00000004685.1.
DR   GeneTree; ENSGT00530000063484; -.
DR   OMA; ASMWEQC; -.
DR   OrthoDB; 4571618at2759; -.
DR   Proteomes; UP000472272; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR015664; P53_induced.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR14399:SF4; P53 APOPTOSIS EFFECTOR RELATED TO PMP-22; 1.
DR   PANTHER; PTHR14399; P53-INDUCED PROTEIN RELATED; 1.
DR   Pfam; PF00822; PMP22_Claudin; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472272};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        152..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   193 AA;  21586 MW;  B518DE0EC9693C91 CRC64;
     MVRCGLACWR CRWLLPLLLG LAIILGIIAL SGRGWLESAE QPYVRKASLW SDCMKANEND
     LNWECRSLMD YSWGRASAAT YLVGFVILCI CFCLAVIAFS IDILRFNFVR GIGGLLFVVA
     AFQIIGLVIY PVMFVEDIPL TGSNMFSWAY GFGWASTVIA IGCAFFFCCL PNWEDEVLGN
     IKPYPIYSSG ERV
//