ID A0A670JWI6_PODMU Unreviewed; 684 AA.
AC A0A670JWI6;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Dynein cytoplasmic 1 intermediate chain 1 {ECO:0000313|Ensembl:ENSPMRP00000027764.1};
GN Name=DYNC1I1 {ECO:0000313|Ensembl:ENSPMRP00000027764.1};
OS Podarcis muralis (Wall lizard) (Lacerta muralis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata;
OC Lacertibaenia; Lacertidae; Podarcis.
OX NCBI_TaxID=64176 {ECO:0000313|Ensembl:ENSPMRP00000027764.1, ECO:0000313|Proteomes:UP000472272};
RN [1] {ECO:0000313|Ensembl:ENSPMRP00000027764.1, ECO:0000313|Proteomes:UP000472272}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30819892; DOI=10.1073/pnas.1820320116;
RA Andrade P., Pinho C., Perez I de Lanuza G., Afonso S., Brejcha J.,
RA Rubin C.J., Wallerman O., Pereira P., Sabatino S.J., Bellati A.,
RA Pellitteri-Rosa D., Bosakova Z., Bunikis I., Carretero M.A., Feiner N.,
RA Marsik P., Pauperio F., Salvi D., Soler L., While G.M., Uller T., Font E.,
RA Andersson L., Carneiro M.;
RT "Regulatory changes in pterin and carotenoid genes underlie balanced color
RT polymorphisms in the wall lizard.";
RL Proc. Natl. Acad. Sci. U.S.A. 116:5633-5642(2019).
RN [2] {ECO:0000313|Ensembl:ENSPMRP00000027764.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00011059}.
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DR AlphaFoldDB; A0A670JWI6; -.
DR Ensembl; ENSPMRT00000029451.1; ENSPMRP00000027764.1; ENSPMRG00000017921.1.
DR GeneTree; ENSGT00940000156032; -.
DR OMA; MGVHFHP; -.
DR Proteomes; UP000472272; Chromosome 12.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12442:SF34; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1; 1.
DR PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR Pfam; PF11540; Dynein_IC2; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000472272};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT REGION 40..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 77433 MW; AF55CA7C864D2DB7 CRC64;
MTTHSSGIML PTYICVEQCL WFFLMIPCLQ EVRTKTLKQK GKDMQDHHQK HDQGITMSDK
SDLKAELERK KQRLAQIREE KKRKEEERKK KESDFQQKKE PTQEDSDLDR KRRETEALLQ
SIGISPEPPL VPTPMSPSPK SVSTPSEAGS QDSGDLGPVG RTLQWDTDPS VLQLQSDSEL
GRRLHKLGVS KITQVDFLPR EVVSYSKETQ TPLSTHRSEE DEDDEELVEP KAQNDSEIET
QEKKQDVKEA PPRELTEEEK QQILHSEEFL IFFDRTIRVI ERALAEDSDI FFDYGGRDVE
EKDGDVQAGA NLSFNRQFYD EHWSKHRVVT CMDWSLQYPE LMVASYNNNE DAPHEPDGVA
LVWNMKFKKT TPEYVFHCQS SVMSVCFARF HPNLVVGGTY SGQIVLWDNR SHRRTPVQRT
PLSAAAHTHP VYCVNVVGTQ NAHNLITVST DGKMCSWSLD MLSTPQESME LVYNKSKPVA
VTGMAFPTGD VNNFVVGSEE GTVYTACRHG SKAGIGEIFE GHQGPVTGIN CHMAVGPIDF
SHLFVTSSFD WTVKLWTTKH NKPLYSFEDN ADYVYDVMWS PVHPALFACV DGMGRLDLWN
LNNDTEVPTA SVTIEGASAL NRVRWGQAGK EVAVGDSEGR IWIYDVGELA IPHNDEWTRF
ARTLVEIRAN RADSEEEGTM EISA
//
