ID A0A671UT40_SPAAU Unreviewed; 290 AA.
AC A0A671UT40;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Claudin 10-like 2 {ECO:0000313|Ensembl:ENSSAUP00010016881.1};
OS Sparus aurata (Gilthead sea bream).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Spariformes; Sparidae; Sparus.
OX NCBI_TaxID=8175 {ECO:0000313|Ensembl:ENSSAUP00010016881.1, ECO:0000313|Proteomes:UP000472265};
RN [1] {ECO:0000313|Ensembl:ENSSAUP00010016881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the claudin family.
CC {ECO:0000256|ARBA:ARBA00008295}.
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DR AlphaFoldDB; A0A671UT40; -.
DR Ensembl; ENSSAUT00010017860.1; ENSSAUP00010016881.1; ENSSAUG00010007749.1.
DR GeneTree; ENSGT00940000166809; -.
DR InParanoid; A0A671UT40; -.
DR OMA; CLYINRI; -.
DR Proteomes; UP000472265; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR006187; Claudin.
DR InterPro; IPR017974; Claudin_CS.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR12002; CLAUDIN; 1.
DR PANTHER; PTHR12002:SF177; CLAUDIN-RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PROSITE; PS01346; CLAUDIN; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000472265};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 242..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 32390 MW; DDD489EE9AE8F04B CRC64;
MRKRLIQIFG FLITSLGWLF VLCTMAMDFW RISQLGGQGG SFIIKVAWYW SNLWKDCFTD
STAVTNCRDF GVLWAVTPYV QGVRGLLMCG LTLGFFAVVL CFVGMDCTYI GGADKTKDKL
LFSGAVFHVA GSFASSIGYD LGPPIFLGLV GCFLILLGAM FYAVTVCRVI CPERYLNSSI
FSLFSVTDEF IPHNKLCICF GLTVKWYMPM EDAHTCPLAP EEEPCTPDTT NPLGCTDLTQ
AQDNQAAPRS QRSLRQRRQK TRKGMPLCSD QMCKHKKQLQ ISLTISTYLS
//
