ID A0A671X2B1_SPAAU Unreviewed; 1006 AA.
AC A0A671X2B1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=UPF0577 protein KIAA1324-like {ECO:0000313|Ensembl:ENSSAUP00010042990.1};
GN Name=LOC115595221 {ECO:0000313|Ensembl:ENSSAUP00010042990.1};
OS Sparus aurata (Gilthead sea bream).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Spariformes; Sparidae; Sparus.
OX NCBI_TaxID=8175 {ECO:0000313|Ensembl:ENSSAUP00010042990.1, ECO:0000313|Proteomes:UP000472265};
RN [1] {ECO:0000313|Ensembl:ENSSAUP00010042990.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the ELAPOR family.
CC {ECO:0000256|ARBA:ARBA00007627}.
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DR AlphaFoldDB; A0A671X2B1; -.
DR Ensembl; ENSSAUT00010045246.1; ENSSAUP00010042990.1; ENSSAUG00010017867.1.
DR GeneTree; ENSGT00940000154983; -.
DR Proteomes; UP000472265; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR039181; EIG121-like.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR InterPro; IPR044865; MRH_dom.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR22727:SF3; ENDOSOME_LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2; 1.
DR PANTHER; PTHR22727; PROTEIN CBG13728; 1.
DR Pfam; PF07699; Ephrin_rec_like; 1.
DR SMART; SM01411; Ephrin_rec_like; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 1.
DR PROSITE; PS51914; MRH; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000472265};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 914..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 659..865
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
SQ SEQUENCE 1006 AA; 110444 MW; 1F3AB8A5F705F8A0 CRC64;
MTRCRALNGP ILFQRLVAVV IGVSHHFRPG HAPTPPMFPF VRAALVFRWN QLHARTESFK
WRLQIASNNY YYQYTECDST GSRWRVSIPL NPGSCSDLPP PTRGTDCSFS CPAGKYLEMS
IQECTPCAAG SYSLGSGLRF DQWDAIPAGF TSLTMGLSTE VSSWTPQGVY LESNRDECTV
SLVYAVHLEK QGSVSFTYQY PDNNIFFEFY VQNEQCQEMA QTDDQKWIKV TNNGEWYTHS
VNLKSGTNIL YWRTTGILVG GKMVKPVLLK NIQIEGVAYT SECFPCRPGW FSPAPGSSSC
EPCPSNTFSI KDAAFCTPCP EHHYSHEGWA ECKVRPPCSE KDYFQIHTAC DSEGKTQVLY
RWVEPKICVE NVTGAVELPA TGQREPCPPC NPGYYNSNDS TCLPCPPGTH SDGTSACTEC
PAGTEPVLGY EYKWWNVLPS NMKTSCFNVG NSKCDDMNGW EVAGDHVHSG ASSSDNDYLI
LTLHVPGFKV PASLSGMTGN EFGQITFVFE TICSADCELY FMMSTTVVES WEGSKGKQSY
THSMTRNASV TFTWAFQKTN QMRRYVTDMV KVYSISVTNV IDGVASACRV CALIPHNSQR
AGSSCVPCPA GFFIDRDTNQ CQECPPNTHL AGRHTYGQDA CVACGPGSVS NKEHSRCYSD
CSFTHTENNR TLTFDLSPLS GVASVTIGPS FTSKGTKYLH LFNMSLCGHE VIHKAAVCTD
NVTVVSNKDD ESDPAQFVNS VDGFICQSTI IPADGRGFRM AISSQSVSLA DTFIGATVDS
VLDGVNATPD LFPENLKDVP DINFFYRSRQ ATASCDQGRS SVITVRCNPE KSDRGEISVP
STCPAGTCDG CTFHFLWESA SACPRCSEDD YHQIEGACKG GVQETLYVWN EPKLCTKGAP
LPARSSVPCE AIALWLKVGV GGGAFVAVLL ISLTCYFWKK NKRLEYKYSR LVMSANKECE
LPAADSCGLA EGEEPDDDVV YTQKPSLLGK LRAIANKVTD FTGQSF
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