ID   A0A671Z4V6_SPAAU        Unreviewed;       174 AA.
AC   A0A671Z4V6;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Lens intrinsic membrane protein 2.2 {ECO:0000313|Ensembl:ENSSAUP00010069969.1};
OS   Sparus aurata (Gilthead sea bream).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Spariformes; Sparidae; Sparus.
OX   NCBI_TaxID=8175 {ECO:0000313|Ensembl:ENSSAUP00010069969.1, ECO:0000313|Proteomes:UP000472265};
RN   [1] {ECO:0000313|Ensembl:ENSSAUP00010069969.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family.
CC       {ECO:0000256|ARBA:ARBA00006864}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A671Z4V6; -.
DR   Ensembl; ENSSAUT00010073238.1; ENSSAUP00010069969.1; ENSSAUG00010027685.1.
DR   GeneTree; ENSGT01050000244814; -.
DR   InParanoid; A0A671Z4V6; -.
DR   OMA; QLCAYRQ; -.
DR   Proteomes; UP000472265; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR003935; LMIP.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   InterPro; IPR004032; PMP22_EMP_MP20.
DR   PANTHER; PTHR10671; EPITHELIAL MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10671:SF106; LENS INTRINSIC MEMBRANE PROTEIN 2.2; 1.
DR   Pfam; PF00822; PMP22_Claudin; 1.
DR   PRINTS; PR01457; LENSMEMPROT.
DR   PROSITE; PS01221; PMP22_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472265};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        67..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   174 AA;  18877 MW;  5595176F94D3401B CRC64;
     MLNTLAGGGT LCGVAALVLL IVSTATDFWM QYRYSGSSAN QGLWRFCINH KCHAHTITVA
     FWDATRAFML LAVLSCFAGV VLGLSAFTNG TKNRRVRTGG IALVLSGFLA LLALAIYTGV
     TVTFFGKRFL DWRFSWSYII GWVAIILAFA AGVFQLCAYQ RTTAEPAPSN NTDS
//