ID A0A672FGC7_SALFA Unreviewed; 460 AA.
AC A0A672FGC7;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=GATA binding protein 2 {ECO:0000313|Ensembl:ENSSFAP00005003485.1};
GN Name=gata2 {ECO:0000313|Ensembl:ENSSFAP00005003485.1};
OS Salarias fasciatus (Jewelled blenny) (Blennius fasciatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Blenniimorphae; Blenniiformes; Blennioidei; Blenniidae;
OC Salariinae; Salarias.
OX NCBI_TaxID=181472 {ECO:0000313|Ensembl:ENSSFAP00005003485.1, ECO:0000313|Proteomes:UP000472267};
RN [1] {ECO:0000313|Ensembl:ENSSFAP00005003485.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A672FGC7; -.
DR Ensembl; ENSSFAT00005003737.1; ENSSFAP00005003485.1; ENSSFAG00005002356.1.
DR InParanoid; A0A672FGC7; -.
DR OMA; AVYPCGS; -.
DR OrthoDB; 685518at2759; -.
DR Proteomes; UP000472267; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 2.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR InterPro; IPR016374; TF_GATA-2/3.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071:SF149; ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2; 1.
DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1.
DR Pfam; PF00320; GATA; 2.
DR PIRSF; PIRSF003027; TF_GATA-1/2/3; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 2.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472267};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT DOMAIN 274..328
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT DOMAIN 328..381
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 146..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 49761 MW; C1CF044621213ABD CRC64;
MDVAADQPRW MHHHAVLNGQ HPDSHHPGLG HNYMEPTAQL LPPDEVDVFF NHLDSQGNPY
YHNPARARVS YSQAHARLTG SQVCRPHLLH SPGISWLDGG KAALSAHHHH NAWAVSPFSK
PSLHHPGSAS PGALSAVYPC SSTSNAVSAS SLTPPSHSGS HLYTFPPTPP KDVSPDPGAA
SPSSSSATRM DEKESIKYQV SLPEGMKMEG SSPLRSSLAS MSAQTPSTHH PIPTYPPYSL
PAAHEYGGSL FHPGSLLGSS SGFCTKNKGK TRSCTEGREC VNCGATSTPL WRRDSTGHYL
CNACGLYHKM NGQNRPLIKP KRRLSAARRA GTCCANCQTT TTTLWRRNAN GDPVCNACGL
YYKLHNVNRP LTMKKEGIQT RNRKMSNKSK KCKRGGDGYE EFSKSLHDKS SPFSAASLAS
HMTMSHLPPF SHAGHMLPTP TPIHPSFGHP HHSNMVTAMG
//
