ID   A0A672HU59_SALFA        Unreviewed;       985 AA.
AC   A0A672HU59;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Huntingtin interacting protein 1 {ECO:0000313|Ensembl:ENSSFAP00005032811.1};
OS   Salarias fasciatus (Jewelled blenny) (Blennius fasciatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Blenniimorphae; Blenniiformes; Blennioidei; Blenniidae;
OC   Salariinae; Salarias.
OX   NCBI_TaxID=181472 {ECO:0000313|Ensembl:ENSSFAP00005032811.1, ECO:0000313|Proteomes:UP000472267};
RN   [1] {ECO:0000313|Ensembl:ENSSFAP00005032811.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SLA2 family.
CC       {ECO:0000256|ARBA:ARBA00010135}.
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DR   AlphaFoldDB; A0A672HU59; -.
DR   Ensembl; ENSSFAT00005033966.1; ENSSFAP00005032811.1; ENSSFAG00005016366.1.
DR   Proteomes; UP000472267; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.20.5.1700; -; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   Gene3D; 6.10.250.920; -; 1.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   InterPro; IPR011417; ANTH_dom.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR032422; HIP1_clath-bd.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR030224; Sla2_fam.
DR   PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR10407:SF14; HUNTINGTIN-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF07651; ANTH; 1.
DR   Pfam; PF16515; HIP1_clath_bdg; 1.
DR   Pfam; PF01608; I_LWEQ; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   SUPFAM; SSF109885; I/LWEQ domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472267}.
FT   DOMAIN          24..151
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   DOMAIN          716..957
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   REGION          960..985
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          370..442
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          467..524
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   985 AA;  109439 MW;  9CA2106179033A43 CRC64;
     LNTNSRKWVI RPSPQSAPLF TWSVKENPSL RQAVSINKAI NTQEVAVKEK HARNILILSE
     CKGAHTFWAA VNRLPLSSNA VLCWKFCHVF HKLLRDGHPN VIKDSMRNKA DLTDMSRMWG
     HLSEGYGKLC SIYLKLLITK MEFHIKNPRF PGNLQMSNRQ LDEAGENDVN NFFQLTVEMF
     DYLECELNLF LGVFSSLDMS RSVSVTAAGQ CRLAPLIQVI LDCSHLYDYT VKLLFKLHSC
     ESLASGTPDP AALTSLFYRS SNLQYFKRLI QIPQLPENPP NFLRASALSE HISPVVVIPA
     ESSSPESEHV VETDDLVDMD VPVLPPPVET KFDDLFGTSA AIDPFNFNSQ NGMRKDDKLF
     FVHRQSDRLR QALSGRISEL EAELAEQSHL RLQAAGESEF LKAELDDLRR VREDTEKEQR
     SLTEIERKAQ ANEQRYTKLK EKYTELVQSH ADLLRKNAEV TRQMTVARAA QDEVEVVRRE
     MQEKVKAAQD AADRQSAEVL SGQVATLESE KAELAQTLSK VEAELVVRGE ELERVQSSLA
     AERETGVKAA ESLQNQLNEK ASREQALESQ LVAARWSSLQ GAVEEAEKII QDSLAQIDDP
     AHISCTSSAD YLASRCQASL DCMDRLQSAK DAFLADDTGV SELVRAVTQC GHLVGDTIVQ
     GSATSHMVPV EQADALSESV KTCGAEALAL LGHMKHRDGL PAADHGKLKA KLRPRGLELQ
     QGELGDLVEQ EMAATSAAVE SAAARIEEML NKSRAVDTGI KMEVNERILG SCTELMQAIK
     MLILSSKDLQ REIVESGRGA ASMKEFYAKN SRWTEGLISA SKAVGWGATV MVDAADMVVQ
     GKGKFEELMV CSHEIAASTA QLVAASKVKA DKDSANLHRL QQASRGVTQA TATVVASTKS
     GKSQIEDRDT MDFSSMTLTQ IKRQEMDAQV LVLELETRLQ KERERLGELR KKHYELAGVA
     EGWGEEEEGE DRRPLGYSEY RDNLR
//