ID   A0A672HV11_SALFA        Unreviewed;       910 AA.
AC   A0A672HV11;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Huntingtin interacting protein 1 {ECO:0000313|Ensembl:ENSSFAP00005032807.1};
OS   Salarias fasciatus (Jewelled blenny) (Blennius fasciatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Blenniimorphae; Blenniiformes; Blennioidei; Blenniidae;
OC   Salariinae; Salarias.
OX   NCBI_TaxID=181472 {ECO:0000313|Ensembl:ENSSFAP00005032807.1, ECO:0000313|Proteomes:UP000472267};
RN   [1] {ECO:0000313|Ensembl:ENSSFAP00005032807.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SLA2 family.
CC       {ECO:0000256|ARBA:ARBA00010135}.
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DR   AlphaFoldDB; A0A672HV11; -.
DR   Ensembl; ENSSFAT00005033962.1; ENSSFAP00005032807.1; ENSSFAG00005016366.1.
DR   Proteomes; UP000472267; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.20.5.1700; -; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   Gene3D; 6.10.250.920; -; 1.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   InterPro; IPR011417; ANTH_dom.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR032422; HIP1_clath-bd.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR030224; Sla2_fam.
DR   PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR10407:SF14; HUNTINGTIN-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF07651; ANTH; 1.
DR   Pfam; PF16515; HIP1_clath_bdg; 1.
DR   Pfam; PF01608; I_LWEQ; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   SUPFAM; SSF109885; I/LWEQ domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472267}.
FT   DOMAIN          31..158
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   DOMAIN          641..882
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   REGION          885..910
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          357..461
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          516..546
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   910 AA;  102387 MW;  4333EFC76F55A654 CRC64;
     MDRVKSSMQQ VPNAIPKVIR RTGGANSLEL EKENFERGQA VSINKAINTQ EVAVKEKHAR
     NILILSECKG AHTFWAAVNR LPLSSNAVLC WKFCHVFHKL LRDGHPNVIK DSMRNKADLT
     DMSRMWGHLS EGYGKLCSIY LKLLITKMEF HIKNPRFPGN LQMSNRQLDE AGENDVNNFF
     QLTVEMFDYL ECELNLFLGV FSSLDMSRSV SVTAAGQCRL APLIQVILDC SHLYDYTVKL
     LFKLHSCESL ASGTPDPAAL TSLFYRSSNL QYFKRLIQIP QLPENPPNFL RASALSEHIS
     PVVVIPAESS SPESEHVVET DDLVDMDPPV ETKFDDLFGT SAAIDPFNFN SQNGMRKDDK
     DRLIEQLTRE IQALKEELES FRLESDRLRQ ALSGRISELE AELAEQSHLR LQAAGESEFL
     KAELDDLRRV REDTEKEQRS LTEIERKAQA NEQRYTKLKE KYTELVQSHA DLLRKNAEVT
     RQMTVARAAQ DEVEVVRREI LSPARPECVS ICCPCVAQEK EQLDQLQELQ RELLSSRAEL
     DSLKSTVSSS QEVTLLSAST GYILITPEIS SPAPKVNCNT VKKLQVFWQH SSHQSRKSLE
     DSIYSRLIVL RLIVFGVFFG LFTDLKPSMF PGLLQKLRPR GLELQQGELG DLVEQEMAAT
     SAAVESAAAR IEEMLNKSRA VDTGIKMEVN ERILGSCTEL MQAIKMLILS SKDLQREIVE
     SGRGAASMKE FYAKNSRWTE GLISASKAVG WGATVMVDAA DMVVQGKGKF EELMVCSHEI
     AASTAQLVAA SKVKADKDSA NLHRLQQASR GVTQATATVV ASTKSGKSQI EDRDTMDFSS
     MTLTQIKRQE MDAQVLVLEL ETRLQKERER LGELRKKHYE LAGVAEGWGE EEEGEDRRPL
     GYSEYRDNLR
//