ID A0A672JTY4_SALFA Unreviewed; 1069 AA.
AC A0A672JTY4;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Huntingtin-interacting protein 1-related protein-like {ECO:0000313|Ensembl:ENSSFAP00005056617.1};
GN Name=LOC115398134 {ECO:0000313|Ensembl:ENSSFAP00005056617.1};
OS Salarias fasciatus (Jewelled blenny) (Blennius fasciatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Blenniimorphae; Blenniiformes; Blennioidei; Blenniidae;
OC Salariinae; Salarias.
OX NCBI_TaxID=181472 {ECO:0000313|Ensembl:ENSSFAP00005056617.1, ECO:0000313|Proteomes:UP000472267};
RN [1] {ECO:0000313|Ensembl:ENSSFAP00005056617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
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DR AlphaFoldDB; A0A672JTY4; -.
DR Ensembl; ENSSFAT00005058335.1; ENSSFAP00005056617.1; ENSSFAG00005026758.1.
DR InParanoid; A0A672JTY4; -.
DR OMA; NREMSDL; -.
DR OrthoDB; 7775at2759; -.
DR Proteomes; UP000472267; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17014; ANTH_N_HIP1R; 1.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 6.10.250.920; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR032422; HIP1_clath-bd.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF10; HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF16515; HIP1_clath_bdg; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000472267}.
FT DOMAIN 23..151
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 777..1018
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1021..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 355..459
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 977..1013
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 575..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1047
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1069 AA; 120585 MW; 9A182833E34D4A8B CRC64;
MNSIRQVPTR VKSRRTEASL GAEREHFDKQ QLSSISKAIN STETPVKEKH ARRIILGTHR
EKGAYTFWSY ALGFPLASSS ILSWKFCHVL HKVLRDGHRN VLQDCMRHHS SLVEIGKLWA
HLHDRYGQLV AIYTKLLCTK MEFHAKHSEI PPNLEVTDEV LERTAGTDIN NVFQLTVEVF
DYMDSELRLA ETVIRQLNTS IAISTLTSGQ CRLAPLIQVI QDCSHLYHFT VKLLFKLHAC
LPADTLQGHR DRFHDQFHSL KSFFNKARDM LYFKRLIQIP RLPDSPPNFL HAASLAKHVK
PVVVIPDEDD AEQQDDDDDE PEPLIEVSDT SASSLQSQPQ LDIFDQAFGP PNGGFDDRDL
QIESLKRDLE LLRAELERVK AEAQRYITQL KSQINSLEAE LEEQRAQKQR ALVENEQLRM
ELEATRRRNA EHESVQTTYI EAEKRAQATE QRYNMLKQKH TELVASHAEL LRQSADTVKM
LSATQQTQEE VERTKQQLSF EVDRIKQESD LKLEEQKFEM EKLKRELEEK MAEVMRIKAT
LQSSEQTSDQ MNSSLTALQA EKERLMRSVS EKEAELSSLR QTAQVQQSSL QQERERNSRE
LGELQGKLQE KTNQEEQIKR KILEEQFALL QGTITEAESI IQDAVAKLDD PLHVRCTSSP
DYLISRAEAT LGSIDKVKKG HADYLSNMGD AGGLLRALTQ FSHLAADTIV NGSATAHMAP
TDHADRLTEN CRDCGSQSLQ YLKELKSKTS LQRADPAAIR AVVQKILHLG QELRPKGRDV
GKEELGDLVD KEMAATSAAI EEAVRRIDEM MNQARKDTSG VKLEVNERIL FSCTDLMKAI
RMLIVASTDL QKEIVESGRG AASIKEFYAK NSRWTEGLIS AAKAVGWGAT ELVESADKVV
LHTGKYEELI VCSHEIAAST AQLVAASKVK ADRNSKKLPV LQQASRHVNE MAANVVASTR
TGQEHLEDKD TMDFSGLSLI KLKKEEIESQ VKVLELETQL ENERIRLGEL RKKHYEIAGV
PLQDASDGNG ETSSLFSPAS TSPKPSKPTL LKKPALAQKP NLPPKATFK
//
