ID A0A672TYQ3_STRHB Unreviewed; 546 AA.
AC A0A672TYQ3;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Glycoprotein nmb {ECO:0000313|Ensembl:ENSSHBP00005006874.1};
GN Name=GPNMB {ECO:0000313|Ensembl:ENSSHBP00005006874.1};
OS Strigops habroptila (Kakapo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Strigops.
OX NCBI_TaxID=2489341 {ECO:0000313|Ensembl:ENSSHBP00005006874.1, ECO:0000313|Proteomes:UP000472266};
RN [1] {ECO:0000313|Ensembl:ENSSHBP00005006874.1, ECO:0000313|Proteomes:UP000472266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jarvis E.D., Howard J., Rhie A., Phillippy A., Korlach J., Digby A.,
RA Iorns D., Eason D., Robertson B., Raemaekers T., Howe K., Lewin H.,
RA Damas J., Hastie A., Tracey A., Chow W., Fedrigo O.;
RT "Strigops habroptila (kakapo) genome, bStrHab1, primary haplotype, v2.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSHBP00005006874.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A672TYQ3; -.
DR Ensembl; ENSSHBT00005008285.1; ENSSHBP00005006874.1; ENSSHBG00005006015.1.
DR GeneTree; ENSGT00950000183188; -.
DR InParanoid; A0A672TYQ3; -.
DR OMA; HGWRKWN; -.
DR Proteomes; UP000472266; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR PANTHER; PTHR11861:SF11; TRANSMEMBRANE GLYCOPROTEIN NMB; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000472266};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 475..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 261..301
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 546 AA; 60700 MW; EA6F80CE4D044DE2 CRC64;
MACSFLSLGF QDVLSQGSTS PVTSYRKLQG WSSDQNKWNE KLYPFWEEGD PRWKDCWKGG
RVTVKLDTDS PALVGSNVTF AVTLQFPKCQ KEDNDGNIVY ERNCTQDFPV SQDQQVYVYN
WTEWIDNCGW ENCTSNYSHN VFPDGRPFPH YPGWRRRNFV YVFHTFGQYY QRTGRSSAVF
SVNTANITLG KHVMAVSIYR RGHSSYVPIA RASAIYVVTD KIPVFVSMFQ KHDRNISDSI
FIKDSPITFD VKIHDPSYYL NNSAISYKWN FGDGSGLFVA SSPVVSHTYT LQGNFTPNLT
VQAIIPVPCK PVTPTAPLPT SAVMTGASSN ADYSITVESV EDIPDEGCHI YRNGYYRNGI
SVVEGILEVN IIQMMSIQMT ESQAENSLVD FVVTCQGSLP TDVCTVVSDP TCQVSKSVLC
DPVTITDECL LTIRRAFEEP GTYCINITLG DDTSQALASA LISVNGGSSP GKTEGVFIFL
GVLAVLAAIG AFVLYKRYKQ YKPIERSTGQ AENHEGLTAY LSNFKAIFFP SNTEKNPLLK
SKPGIV
//
