ID   A0A672U0T5_STRHB        Unreviewed;       923 AA.
AC   A0A672U0T5;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Nuclear export mediator factor {ECO:0000313|Ensembl:ENSSHBP00005007686.1};
GN   Name=NEMF {ECO:0000313|Ensembl:ENSSHBP00005007686.1};
OS   Strigops habroptila (Kakapo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Strigops.
OX   NCBI_TaxID=2489341 {ECO:0000313|Ensembl:ENSSHBP00005007686.1, ECO:0000313|Proteomes:UP000472266};
RN   [1] {ECO:0000313|Ensembl:ENSSHBP00005007686.1, ECO:0000313|Proteomes:UP000472266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jarvis E.D., Howard J., Rhie A., Phillippy A., Korlach J., Digby A.,
RA   Iorns D., Eason D., Robertson B., Raemaekers T., Howe K., Lewin H.,
RA   Damas J., Hastie A., Tracey A., Chow W., Fedrigo O.;
RT   "Strigops habroptila (kakapo) genome, bStrHab1, primary haplotype, v2.";
RL   Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSHBP00005007686.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   AlphaFoldDB; A0A672U0T5; -.
DR   Ensembl; ENSSHBT00005009250.1; ENSSHBP00005007686.1; ENSSHBG00005005239.1.
DR   GeneTree; ENSGT00390000018516; -.
DR   Proteomes; UP000472266; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472266}.
FT   DOMAIN          515..625
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          823..913
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          404..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          746..790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          284..331
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          470..497
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        405..419
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        752..776
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   923 AA;  105073 MW;  8A96CC2B162A8A9B CRC64;
     MYLLFDSLLG MRVNNVYDVD NKTYLIRLQK PDCKATLLLE SGIRIHTTEF EWPKNMMPSS
     FAMKCRKHLK TRRLVSVNQL GIDRIVDFQF GSDEAAYHLI VELYDRGNIV LTDHEYIILN
     ILRFRTDEAD DVRFAVRERY PVDSAKAPAP LPTLERLTEI ISNASKGEQL KRVLNPHLPY
     GATLIEHCLV ETGFSGYVKI DQHMENKENV EKVLTALEKA EEYMTLTGNF SGKGYIIQKR
     EKKPSLEPDK PAEDIYTYEE FHPFLFSQHS KCPYLEFDSF NKAADEFYSK LEGQKIDLKA
     LQQEKQALKK LENVRRDHEH RLEALQQAQE ADKMKGELIE MNLEIVDRAI QVVRSALANQ
     IDWTEIGAIV KEAQAQGDPV ASAIKELKLQ TNHITMLLRN PYVLSEEEEE EEDADLEKEE
     TEEPKGKKKK NKNKQLKKPQ KNKPLLVDVD LSLSAYANAK KYYDHKRHAA KKTQKTVEAA
     EKAFKSAEKK TKQTLREVQT VTTIQKARKV YWFEKFLWFI SSENYLVIAG RDQQQNELIV
     KRYLKPGDIY VHADLHGATS CVIKNPSGEP IPPRTLMEAG TMALCYSAAW DARVVTSAWW
     VSHNQVSKTA PTGEYLTTGS FMIRGKKNFL PPSYLMMGFS FLFKVDESCV WRHREERKIK
     VQDEDLETVS SSASELVSED VELLGMVAVM GVLCTADRRD CLGFGIEFPA LCYGSLLCFL
     LQSKMKKMKE KYKDQDEEDR ELIMKLLGSA GSNKEEKGKK GKKGKTKEEP AKKQQQNPKA
     VRHGARGGKE SLPAGVVLHE SQDPALEEQQ DEKVSTPLPA QEGEALLDSL TGQPHPEDIL
     LFAVPICAPY TAMTNYKYKV KLTPGTQKKG KAAKIALHNF MQSKEASARE KDLFRSVKDT
     DLSRNIPGKV KVSAPHLLNK KKK
//