ID A0A673CEN2_9TELE Unreviewed; 448 AA.
AC A0A673CEN2;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Internexin neuronal intermediate filament protein, alpha b {ECO:0000313|Ensembl:ENSSORP00005051774.1};
OS Sphaeramia orbicularis (orbiculate cardinalfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Kurtiformes; Apogonoidei; Apogonidae; Apogoninae; Sphaeramia.
OX NCBI_TaxID=375764 {ECO:0000313|Ensembl:ENSSORP00005051774.1, ECO:0000313|Proteomes:UP000472271};
RN [1] {ECO:0000313|Ensembl:ENSSORP00005051774.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A673CEN2; -.
DR Ensembl; ENSSORT00005053007.1; ENSSORP00005051774.1; ENSSORG00005023179.1.
DR Proteomes; UP000472271; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652:SF18; ALPHA-INTERNEXIN; 1.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000472271}.
FT DOMAIN 57..367
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 389..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 75..193
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 251..345
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 397..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 51877 MW; B9D878C299BD4897 CRC64;
MKSKPSVIFS KYTSSFCLVQ VFLRKSGRSF SSMPLETFDL TQSTVLNNEF KIIRTNEKEQ
MQGLNDRFAM FIEKVRNLEQ HNKVLETELI TLRQRQTEPS RLAELYQQEI RELRSQLDEL
NGEKSHLMIE RDSIEDELQK VRGKYEEEFR AREEAEATLK AFKKDVDDAT MVRLDLEKKV
ESLLDEINFL RKVHEEEVAE LTDMIHAAQV SVEMEVSKPD LTSALKEIRG QYESMASKNL
QSAEEWYKSK FADLSEQANR SNEAIRASRE EMNEFRRQLQ SKTIEIEGLR GTNESLEKQL
REMEDRHSVE IGNYQESMAE LENELRTTKN EMARHLREYQ DLLNVKMALD IEIAAYRKLL
EGEETRIGTG ITYPTPSIGS SGGGYSYQTH IYSSSGKGSK KESKDEEQHQ SKSVSKVAQR
EIYEESVVST KKMEKQQEAS GIPTNQKN
//
