ID A0A673UTC4_SURSU Unreviewed; 503 AA.
AC A0A673UTC4;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040931};
DE AltName: Full=Nuclear domain 10 protein NDP52 {ECO:0000256|ARBA:ARBA00041519};
OS Suricata suricatta (Meerkat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Herpestidae; Suricata.
OX NCBI_TaxID=37032 {ECO:0000313|Ensembl:ENSSSUP00005028733.1, ECO:0000313|Proteomes:UP000472268};
RN [1] {ECO:0000313|Ensembl:ENSSSUP00005028733.1, ECO:0000313|Proteomes:UP000472268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dudchenko O., Lieberman Aiden E., Tung J., Barreiro L.B.,
RA Clutton-Brock T.H.;
RT "A Chromosome-scale Meerkat (S. suricatta) Genome Assembly.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSUP00005028733.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}. Cytoplasmic vesicle, autophagosome
CC membrane {ECO:0000256|ARBA:ARBA00037854}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00037854}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the CALCOCO family.
CC {ECO:0000256|ARBA:ARBA00037963}.
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DR AlphaFoldDB; A0A673UTC4; -.
DR Ensembl; ENSSSUT00005032799.1; ENSSSUP00005028733.1; ENSSSUG00005018192.1.
DR Proteomes; UP000472268; Chromosome 17.
DR GO; GO:0000421; C:autophagosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd21968; Zn-C2H2_CALCOCO2; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 6.20.250.40; -; 1.
DR InterPro; IPR041641; CALCOCO1/2_Zn_UBZ1.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR31915:SF4; CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR31915; SKICH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF17751; SKICH; 1.
DR PROSITE; PS51905; ZF_UBZ1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000472268};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01253}.
FT DOMAIN 476..501
FT /note="UBZ1-type"
FT /evidence="ECO:0000259|PROSITE:PS51905"
FT COILED 135..348
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 503 AA; 57674 MW; 0F9CED230EC230DE CRC64;
MEETVEDPPT SAVLLDHCYF SQVIFNSVEK FYVPGGDVTC YYTLTQEFIP RRKDWIGIFR
VGWKTTREYY TFMWVTSPSD LNRELAKKQE VKFKAYYLPK DDEYYQFCYV DQDGVVRGAS
IPFQFRPENE EDILVVTTQG EVEEIEQRNK ELCKENQELK DSCVNLQKQN SDVQAELHKT
QEELETLKSA TQKLEEKVKA QKDSWEAELL QLKEQNQKMS SENKKMGVRV EELQAQLSKQ
EKEMAKLVQG DQDKTEQLER LNEEKSQLLL TLTQQREHQK KLEQRVEVMK QEETAALKKQ
QAFTDENSGL SKKLSENKIM YNALQREKER LERENDLLKK ENNRLLSYMG LDFDSLSYQV
PTADQGGAGR NPALVYGNPY SGIQESSAPS LFGKAAGSVG SKPEAVEGGR RKHCSSISFL
VQITCERSLA PGLGRRCELG SHPNKLAARK CPTCKSDFAD DILDPALEPQ HPQPLCLNCP
ICGKTFPAKD KQIFEDHVYC HSL
//
