ID   A0A673WAD4_SALTR        Unreviewed;       520 AA.
AC   A0A673WAD4;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Poly(A)-specific ribonuclease PARN-like {ECO:0000313|Ensembl:ENSSTUP00000005697.1};
GN   Name=LOC115147670 {ECO:0000313|Ensembl:ENSSTUP00000005697.1};
OS   Salmo trutta (Brown trout).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8032 {ECO:0000313|Ensembl:ENSSTUP00000005697.1, ECO:0000313|Proteomes:UP000472277};
RN   [1] {ECO:0000313|Ensembl:ENSSTUP00000005697.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the CAF1 family.
CC       {ECO:0000256|ARBA:ARBA00008372}.
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DR   AlphaFoldDB; A0A673WAD4; -.
DR   Ensembl; ENSSTUT00000006056.1; ENSSTUP00000005697.1; ENSSTUG00000002721.1.
DR   GeneTree; ENSGT00940000153167; -.
DR   Proteomes; UP000472277; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR   CDD; cd12428; RRM_PARN; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR014789; PolyA-riboNase_RNA-binding.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR006941; RNase_CAF1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR15092; POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1; 1.
DR   PANTHER; PTHR15092:SF44; POLY(A)-SPECIFIC RIBONUCLEASE PARN; 1.
DR   Pfam; PF04857; CAF1; 1.
DR   Pfam; PF08675; RNA_bind; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000472277}.
FT   DOMAIN          368..445
FT                   /note="Poly(A)-specific ribonuclease RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF08675"
FT   REGION          146..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          448..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        448..465
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..520
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  59813 MW;  E22A8F80F7796873 CRC64;
     MLADCCFCVT DFKDSLNTVY SAIEEADFLA IDGEFSGISD GPNVSALTNG LDTPEERYMK
     LKKHSMDFLL FQFGLCTFTY DQAESNYVIK TFNFYIFPKP FNRTSPDTKF ICQSSSIDFL
     ASQGFDFNKV FRHGIPYLNQ EEEVQLREQY EERRSQSNGS GNPSYISPNS NKGPGSIPEE
     HREYIGRKER YIQISKVDDE ERKRRERQKQ EREQVTFRWD SSLFPLSPTQ GKLVVGHNML
     LDVMHTIHQF YCVLPEVQTR TIYMNTMVYF LFHLYLNRIF ILTFPFKSPK VVTAEGFPSY
     DTAQEQLHEA GYDAYITGLC FISMANYLGT FLTPPRAHIP SQSKLIQPFV NKLFLMRIID
     IPYLNISGPD LQPKRDHVLY VTFPKEWKTS DLYQLFSAFG NIQVSWIDDT SAFVSLSQTD
     QVQIAINTSR YAESYRIQTY AEYVQGRQQV RESQGHSTQP SLGKRCVSPI QEEQPTDGEA
     QRSHADGWSG YTHSHTHSDT GSKKIRTDGK DAHTHTHSPA
//