ID A0A674AAH5_SALTR Unreviewed; 466 AA.
AC A0A674AAH5;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Desmin {ECO:0000256|ARBA:ARBA00040601};
GN Name=LOC115155439 {ECO:0000313|Ensembl:ENSSTUP00000055301.1};
OS Salmo trutta (Brown trout).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8032 {ECO:0000313|Ensembl:ENSSTUP00000055301.1, ECO:0000313|Proteomes:UP000472277};
RN [1] {ECO:0000313|Ensembl:ENSSTUP00000055301.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004135}. Cytoplasm, myofibril, sarcomere, Z
CC line {ECO:0000256|ARBA:ARBA00004216}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A674AAH5; -.
DR Ensembl; ENSSTUT00000057854.1; ENSSTUP00000055301.1; ENSSTUG00000023433.1.
DR GeneTree; ENSGT00940000155522; -.
DR Proteomes; UP000472277; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652:SF2; DESMIN; 1.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Reference proteome {ECO:0000313|Proteomes:UP000472277}.
FT DOMAIN 108..416
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 17..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 112..260
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 300..394
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 466 AA; 52983 MW; 2B7C5E982691714E CRC64;
MSKSFSSQSA QSASSYRRTF GSGVGSTPGM SSMFSHGGRG SSGSSGSAHM SSRVYEMTKT
SARPSYSSGS IRSSSGGAMR SYAGMGEKLD FNLADATNRD FLDTRTNEKA ELQHLNDRFA
SYIEKVRFLE QQNATLVVEI ERMRGHEPTR VAEMYEEEMR ELRRQVEGMS NDRARMEVER
DNLADDLQKL KLRLQEEIHQ KEDAENNLSA FRADVDSATL ARLDLERRIE SLQEEITFLK
KIHEEEIHEL TSQMQETSVQ VQMDMSKPDL TAALRDIRMQ YEGIAAKNIS EAEDWYKSKV
SDLNQAVNKN NDALRQAKQE SMEFRHQIQS YTCEIDSLKG TNESLLRQMR EMEDRLGNEA
GGYQDSVTRL EAEIAKMKDE MARHLREYQD LLNVKMALDI EIATYRKLLE GEEKTSPDVG
RSAEVHSKKT VLIKTIETRD GEVKSTHRRY IASIIGFVPS NTLFPI
//
