ID   A0A674E7H7_SALTR        Unreviewed;       883 AA.
AC   A0A674E7H7;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Transmembrane protein 245 {ECO:0000313|Ensembl:ENSSTUP00000104020.1};
GN   Name=TMEM245 {ECO:0000313|Ensembl:ENSSTUP00000104020.1};
OS   Salmo trutta (Brown trout).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8032 {ECO:0000313|Ensembl:ENSSTUP00000104020.1, ECO:0000313|Proteomes:UP000472277};
RN   [1] {ECO:0000313|Ensembl:ENSSTUP00000104020.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000256|ARBA:ARBA00009773}.
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DR   AlphaFoldDB; A0A674E7H7; -.
DR   Ensembl; ENSSTUT00000111527.1; ENSSTUP00000104020.1; ENSSTUG00000046266.1.
DR   GeneTree; ENSGT00390000001667; -.
DR   InParanoid; A0A674E7H7; -.
DR   OMA; CVHFFWK; -.
DR   OrthoDB; 3080970at2759; -.
DR   Proteomes; UP000472277; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR   PANTHER; PTHR21716:SF4; TRANSMEMBRANE PROTEIN 245; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472277};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        62..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        198..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        237..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        461..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        655..674
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        779..798
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        818..839
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   883 AA;  97282 MW;  1458DD9B5B3BE949 CRC64;
     MADEEDSGPE AEPAPSSPAE TPSSARPHYV SFSESVQPAV GMMSQLLSQP SSLKFDKNIK
     QAFYNTGAMI FVAICCGAAV LVFFILEAFL RPLLWAVLCG TFLHPFKHSL ARLGRSWLNG
     LQDTGTPILL GTLLVPVWCF NHGVDFLAGL VLERLTVLLV IGAGAPLIYF FYLFWSVIGM
     QVIIGHVCDV IGSALDCFHS VWVMTVVLGY VLAVVCKWSP GTERYLRTMS VPVWTILLFY
     LVSLTGSWRV PVFVIVVTLL IVGSQEKPPV PGNSGELSGQ VLSFAANTIY MAISCSNLHL
     GPERETSTSS VSADGVDSVG PGPSGPPSVF PFPLQARPEL GGLFQKKGSQ RASDIYFVLL
     AWAFVLVQVW LNLWMLQLLP IPVAVWVLKK LVVHFGLKQF AEKTLSSWWV GLEKFGRERQ
     DAIMPGPIKG LVQFLLRVDT KLWHWLNKQM VIWLERSLDK LISIFIIFLL VTGTLLMGLL
     LTAMVHHESV HIIEVTSNLI NETVSSHPEW ANWLPEAQVI QKAMNSAATN VYQHGREWIT
     FKLHKMLGEK GNHTAVIEKQ VLELWDRLYH SWFVKNVTHT GGRNRSGGQK LVQRQNSWLG
     EILDWQDIAS FAQENIETLL SIVESLWVVM SRNVGLLIST TTTLLTVLFH SGTALLNFAL
     SLVIFLTTLF YLLSSSGEYY EPVKWVISLT PLSQPGPSSN IIGQSVEEAI RGVFDASLKM
     AGFYGLYTWL THTIFGIHIV FIPSALAAIL GAVPFLGTYW AALPAVCDLW LAQGEGVKAL
     LLLLFHLLPT YFVDTAIYSD ISGGGHPYLT GLAVAGGAYY LGLEGAIIGP ILLCILVVAS
     NIYSAMLMSP NSAQPTPVQS TWPLHPARSF MDTTPSVLKR MSE
//