ID A0A674EZR0_SALTR Unreviewed; 416 AA.
AC A0A674EZR0;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Dynein axonemal assembly factor 4 {ECO:0000256|ARBA:ARBA00024430};
GN Name=dnaaf4 {ECO:0000313|Ensembl:ENSSTUP00000113833.1};
OS Salmo trutta (Brown trout).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8032 {ECO:0000313|Ensembl:ENSSTUP00000113833.1, ECO:0000313|Proteomes:UP000472277};
RN [1] {ECO:0000313|Ensembl:ENSSTUP00000113833.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, neuron projection
CC {ECO:0000256|ARBA:ARBA00004487}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Dynein axonemal particle
CC {ECO:0000256|ARBA:ARBA00024190}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A674EZR0; -.
DR Ensembl; ENSSTUT00000121834.1; ENSSTUP00000113833.1; ENSSTUG00000050241.1.
DR GeneTree; ENSGT00390000004930; -.
DR OrthoDB; 167568at2759; -.
DR Proteomes; UP000472277; Unplaced.
DR GO; GO:0120293; C:dynein axonemal particle; IEA:UniProtKB-SubCell.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003341; P:cilium movement; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd06469; p23_DYX1C1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR037894; CS_DYX1C1.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46492; DYNEIN ASSEMBLY FACTOR 4, AXONEMAL; 1.
DR PANTHER; PTHR46492:SF1; DYNEIN AXONEMAL ASSEMBLY FACTOR 4; 1.
DR Pfam; PF04969; CS; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 3..87
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REPEAT 361..394
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 189..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 105..172
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 189..214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 416 AA; 47616 MW; 5CD86D62FA82F520 CRC64;
MPLIVKDYTW TQTETIVYIN VPLKGVKVGK VDIFSTDEYL KVHFPPFLFE AFLSEPIDDD
KSTAKIGNGV AVFTLQKKKE RLWEHLVINN NDKDKLREIR ERALLKAQEK LAAESKAKAT
KTQEERKYAL ETMMKLEEEG RARIQKMKDD ECEKATAQLE AWKLKQRQIA EEEAQLKLQS
QRIKVDKQSK SEKIYVPRTS DQSKVKHDQK NSVQSISKKK QVDLPAPRST GNIQIKFTPR
VFPTALRESR VLEEEEWLQK QAEARRAINV NLAELKDLTE EERNPDWLKE KGDKLFATGN
YLAAINAYSL AIKLNRKIPA IYSNRAACHL KLRNLHKAIE DSSWALDLLT PPVAGNAGAR
TRAHVRRGTA FCELELYTEG LQDYQAALTI DPQNETLQAD THKIRQIIQG SAPCPE
//
