ID A0A674H4L4_TAEGU Unreviewed; 4468 AA.
AC A0A674H4L4;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Pericentrin {ECO:0000313|Ensembl:ENSTGUP00000030448.1};
GN Name=PCNT {ECO:0000313|Ensembl:ENSTGUP00000030448.1};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000030448.1, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000030448.1, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000030448.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR Ensembl; ENSTGUT00000020113.1; ENSTGUP00000030448.1; ENSTGUG00000028465.1.
DR GeneTree; ENSGT00730000110871; -.
DR Proteomes; UP000007754; Chromosome 7.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR PANTHER; PTHR44981:SF2; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
DR SMART; SM01188; ELK; 8.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 383..401
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 446..467
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1128..1146
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1248..1269
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1423..1446
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1560..1581
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1589..1607
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1880..1902
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT REGION 26..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3444..3465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4039..4062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4092..4129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4367..4434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 116..206
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 231..286
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 352..503
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 754..798
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 828..1166
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1202..1274
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1365..1477
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1529..1556
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1651..1722
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1778..1829
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1869..1896
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1958..2119
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2213..2286
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2407..2434
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2477..2518
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2546..2733
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2759..3044
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3073..3107
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3168..3209
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3668..3836
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3866..3904
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4209..4236
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 44..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4101..4129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4379..4418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4468 AA; 518707 MW; 57B77B7F4932C358 CRC64;
MEAPEEARRR KLEAGRAKFA YFRQRKAKGD VAQSQKKAAK RKGSAVHAHD LPKEEHPVAA
RDAGKGLEGQ AEDTNLPEAA TEAQGSTDLF SWEPLDDHAT EKDRINSAAE YSEADAQMCQ
ARIAELESRL LEKQEAVERL TVQMDELQDQ LTQHNDSMQL QETTVQEQNE IIRKLTTCLQ
QAKKDRDELQ EEASRVAHQI HDLQLQLHQV TELLRSKSLR KNEGLEAQQQ MSLFQDRLRE
QNAHLEILRE KAHDLEVQLE SSQKNTKDKE NLLAQMEEDM KDSMQKLYKS IDEKEQFIKS
LQDLLTSERF GLSILQHTLS LRDSEITELK KEIALSKVKE QQHIEELKIS HEKDICRQLD
NLRNELEKCH RREIAEAKQV YEEEIILKYK NELEQLKKEL CALNSEEHIQ NLNGIIIDLN
VRLRESEISK ENLRKKLENQ QEGFKREKSE MESKYKDVID GLKHQLSYAE EQVKESQRYK
KEKQSLNEEI QKLNSYIQEL NEKQLYEAKK PIDVRQKHDG EIVSNKKLLE LRENQILPGM
SQLQGADLEE MWDRANLSEG RDEPVLQPEL EFQYDSSRDQ LEETKNLEIT NVNGSGEGEN
LSEGPLSELG LFSGDEGILA KYLVSTETPE DSYGSSSSEG HAIEEGRCSM YGLDNSVLLE
PGRDFVSSPL NSSLEEGTCL SGLAQDIFEG AEVRAEAFVS CVSDGSLQQN KIGEHSDIED
DEVMCLAERH LKPAELLHQE SALEMPYQDT QEAVGNWEKA MSELSHMHAK LEEEHEARIR
CEKELLRKME KEKELENKHM LLVKQQREDG GQPALTQVSN SSVWLEMVKD LQEEREMLMM
QLRTQEQLVR DAQEQKTASD SVTNEVQDLF GRQLAALQSQ RDGMESQLNA QKAKNQRIAE
LLSQKTISEG TLLKELELLK AEINNKEQNL VLLLKEKTAL RERLSNVEED LLKAEKALAE
NASMLDDLEK NIHELNAEMK NIKEIQECER LSYEDRLNIS NQEINKLTAE IKEKTAEYSE
EKGQLTEEIA QLKKAHLELE ARLQESCQAA QEAQSKMEKH YREEMDKMET QHLAELTEVS
LAHEREIKEL NAEIQDKVEE QQKLEEKRKE EIAVIKKVHE REHDREISEL AAKHSEEMEK
LRAELKEEQR HLLDELRQQM AATHKAEHEQ AQLQSQTLHS LELEALRLTL NNMHTSQLEL
TQSNLRKEKE TALMELREML NDKRAQEVAI LQSRHQLEWE RIKEQCLKEK EDLKSKYQQE
LVDQRKKIES EMEETHVQAL ETLKRDWKLE SDRRLQNVCE ELCEKHQAEM IALQKSLEMD
LEKVRAELGL LSVENVQSKM KCIELERQHQ IAITKLQEQL QAEHHQILED IKMKSQEKEQ
NLQKELDQLQ VKHEQLKVQS QEEIRQLWSQ LDSTRANRQE LSELKEQLQA RASRVEEIEC
LKQEFEQQCQ QRNREHKAEL EQLRLFFENK LIVAEENYKK ELTLLHQRPQ ELTDCSLPEL
EMSQDQAGDI SSSVTLFEET AEKERSVALG QLDQQLEQQQ EELACLQLQL AEQHRHELDS
LRSSLALQYK EDLMKMKMHL SDKYAAETEA LKRKHGLELE QLHAQLSEEQ SKEITKLHLQ
SVQNVARQVE VEVAERVSVL EEEHKAKLAL SSSEKQHIAE LSEEIRHLKE ELIKQKDFSE
QNEKHLKEEM EKVKYKIAED HKKELREEVQ KIENMYKEKE KKWQCESEAQ RILAEEKLSL
LRIELQTRAE SEKQNLQKHF ELREAEMIQL QDHQAAKILD LEKLVKEQQN NLQQLEDSLA
GAQAVQKAQQ QYEADLEAAK ALMAKEMEKT TLCLQEECAL KLLEAQNKFM EEHQAMTQKF
TTEQEILLQK LKKKHMDELE LQSQQLEEKH RQQILSLTAD FQAKHQAEIE TLKSTLESKQ
QIQLERCVAE LQTKHQAQID ELEVKHLSNL DSLESSYLSE IQTIRDEHSQ ALEKLQLQHR
EQLQEQDKIR QAQLLQEIEM LKLKHAEELQ LSQNNLKIEL ATVNLENLKT MALEAEEAHK
DELNTALQNQ RQLLEEEKRL ALDLLREEVL QMEEKHRKAL QELRDLHEAD IRKHKEEYSR
ELEEQLGKLK AEHECEQELY ASASASEVKS VRAALLAQFE EVKLKQQLQF QEEIELLKCQ
SEVLLEQQIS QLKDEFEAEK KASLHDKEQM LIQEREKVQA AHQKEQEMLS AQLQERAAII
NQLEEKVASL KHEIEETNSE LETLLPWRGR ENQEGRNLVA LLRSDIEQSK EEREKLRESY
QHVLKLLMEV VKATVVIEDL ICSKIGLCLD DSLASGDSKE AQSIMEEMGF MQYFKAKENH
HLEKASLLSV EELLDETLTE HNQLSPGTDE VSELSQYLCE SVFAKPELAC ESEETILKIC
HRLRTAVERL LELVTESTKQ LEKMHENHAQ FEEEFSRRNR ETAQVVSQHQ ELMECLSEES
EAKNQLALEL HKAEGIIEGY VAEKAALEEA LNLKEESERR LVVELENMRE RFQELTQEQA
ILGLLKEVEF LSKEKLELQC QAEKDHSNLR SQMKVLEVEL EEQLQSNQDL ATKLLEITEL
KQQIEVLEKQ LKNQRQFMDE QAIEREHERD DFQQEIQKLE EQLKLSAKSQ TSGQSREHRN
YELILQVESL QAEIKEKMDD YNKLLLEKER KHQEIAARDK EIENLVAQIQ ELKLRGAEVS
KTVHSLEQQL QKMKKVETEL KQDKEALQQQ QYNNLIQISA LQSKLDEARH RVPVDGTSAP
VLKEQLQAEQ EALQAKEREI ASLLDQVEQY KDNLSKKDEE ILQLNLQLEI QKNFSTSNII
QLQAENAHLQ EDLTKLHVKQ SQDLGISDSS ALSFPQALLE EKNQEIDHLN EQMKRLQHEL
QNALENRVAE DQRPEIEELR SLVEHLRLDQ ERLRKDKDEE VEQLHGVIEK LQKELAQFGP
VCHEDSDNPV YFYEVALEKS VENLQNELKK ELVDCQGDAD ANRRNESVHS KMRELQQELE
LVSASKEALQ EQLERKELQL KTEVEALEKK CQRLRESSEQ SVAELTSLRI QHQALQEEYR
VSQTLLSQRE AETKMTTSRV QELEDKVREK EANILEKEMQ IKTMADQREA DTTELQYLTE
KAAELQTELE KRGASQAQDV YNLQLEVSRL DFQVQALNQK EVAYLREIKE LQGSTAKLKG
EIKAHMKELE ALRLERDEIL SQLESCKLEE QVGHEETQFL KPFCQSKRKD GDFKNGMQEL
EANIDQSFGV LASPTAKLEK DDAMFDVTFH NKNPKTQMKQ SQENIFCQEL DMIHSSEGDQ
DLKKHCQQML EIHQTPDSPK HNLSIDKETP KDYQNLIASM SSWGSPEIMR KQDISMELQP
VLHLTPFSEA ENTDFQIVHT RSSLEAENSI SLGFSNLDEN GSGDAAVGVD RRSPAFSEST
YTVDDDEAME KNLLMREADN LTLTPSDLQD DERSRASAMS DGCGSNTSSN LAANLKQELQ
TSDHLDANVM AYLRYRGIIP DIMESMKEKE ILSPQMKTVL KMVYEESRKI LALSEHPFAF
RELKNVPQTQ VAMEGWQKEG LSLLDAIQSL KDYLSKVADR GDKETSGVAA DWRGELLQAV
QSVFEKERSM LQIDLKSHFS NPASGDTSSF GEKLEYIMKQ QEEQRQMVVE HLFSSDRNSL
LSEIQDLRAQ LRMTHLQNQE KLQQLQETLT KAEDHGNKQE HQLRRKVELL EYKLQQEKSI
VSDLQSTLSE EQRRSSETCD LLNQEKASLK SELSGSMQEN ERLQKSLEEL QREINNLSVQ
LEKKEKDLAA ALEDLQAEQL KGSKLRDWFE EQQRQQRKAE DEKTKAMEEL QAALDVQLVQ
NCQLAVSLEH ERTVTDNLRK ELQIEHSRCE ALLAQEHNKL RELQKNLDAE KNRSSELLDS
LNHERVLTEQ LSMRVKEGAS CQHRESLLEQ AFVRELQAQL EEERAQTMEL AAVIEKMQHK
AILSKRQLEA EVQMCHEETQ KEKEVSDKLR ATLESLQAQK QEVIRSLEAQ REREVKLKVD
WEQLQSLFKL LKEQDKNRKE EREREQKQQQ QTELQKQKDW QRDQERLQNL ERQHQRDEQR
IKELQEILAV LRERERNPPT QSCQEELLCT SSKDGSATQP VTKETEKPHL QQQQQQLEKI
RQQLLFVVVH LNEFIHKTLD KTVNDWSASN DEAVASLLQT LRELKSDLSP PTSQVRSTSD
ADPVQELERE AWQRERNTLQ NMLKQAESQL AKAKAEIENK PVAEISNPKL QRLYRKYIRA
ESFRKALVYQ KKYLLLLLGG FQDCEQATLS LIARMGIYPS ADLQLSGSRS RPFTKFRCAV
RAIIAISRLK FLVKKWNKVG RKSTQGESIS HSIGGNTASG ARTEVLKEQQ PPACPVSSPP
TQDRDTGLCH RTSCAARFTS LSPRSSSRSH NRLHLSPSSA PDKSFVPPQD PEQSLTEYIH
RLEAIQQRLR GLQPGQVLGS PHQRNLKK
//
