ID A0A674N1D1_TAKRU Unreviewed; 597 AA.
AC A0A674N1D1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Metastasis associated 1 {ECO:0000313|Ensembl:ENSTRUP00000067057.1};
GN Name=MTA1 {ECO:0000313|Ensembl:ENSTRUP00000067057.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000067057.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000067057.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000067057.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A674N1D1; -.
DR Ensembl; ENSTRUT00000079295.1; ENSTRUP00000067057.1; ENSTRUG00000009012.3.
DR GeneTree; ENSGT01030000234573; -.
DR Proteomes; UP000005226; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04709; BAH_MTA; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF5; METASTASIS-ASSOCIATED PROTEIN MTA1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Zinc {ECO:0000256|ARBA:ARBA00022771};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 2..145
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 146..257
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 264..299
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 323..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 597 AA; 66952 MW; 8C0BF589831A381F CRC64;
VCVTLYRYYV YFENSSSNPL LIRRIEELNK TANGNVEAKV VCFYRRRDIP GTLIALADKH
ARELEEEMEN PEMVNLPEKQ KHQLRHRELF LSRQLESLPA THIRGKCCVT LLNETEALKS
YLDREDAFFY SLVYDPQQKT LLADKGEIRV GNKFQADITD LLKEGEEDER DLEKLEEKIW
EPSSSLSEKQ IDQFLVVARS VGTFARALDC SSSVRQPSLH MSAAAASRDI TLFHAMDTLH
ATGYDMTRAI AALVPQGGPV LCRDEMEEWS ASEANLFEEA LEKYGKDFTD IQQDFVSSKK
YTNPHYYFSI KLKQVYIPNY NKPNPNQLSN NTKPALLNGA AGAAGSGPPG SGPTPGLGRA
CESCYTSSSY QWYSWGPPNM QCRLCASCWT YWKKYGGLKM PTRLEGERPG PNRNSMSPHG
LPLRHSSSPK FAVKTRQAFY LQTTGLTRMA RRLCQDIIRP GYLARHPYLP VNTAAIKAEC
ALRLPDSPKK PSPVKPVKRK PLESVVRYLV AHPRPAKPDP PVRGGSISTG SLTPIKSSPI
LNNGSPTILG KRTYEQHNGL DGTKSKSLTP QWDIMAKRVS DAGRPSVSLQ DEVHELD
//
