ID   A0A674N8M9_TAKRU        Unreviewed;       631 AA.
AC   A0A674N8M9;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Dynein cytoplasmic 1 intermediate chain 1 {ECO:0000313|Ensembl:ENSTRUP00000069943.1};
GN   Name=DYNC1I1 {ECO:0000313|Ensembl:ENSTRUP00000069943.1};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000069943.1, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000069943.1, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000069943.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC       {ECO:0000256|ARBA:ARBA00011059}.
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DR   AlphaFoldDB; A0A674N8M9; -.
DR   Ensembl; ENSTRUT00000065850.1; ENSTRUP00000069943.1; ENSTRUG00000020585.2.
DR   GeneTree; ENSGT00940000156032; -.
DR   Proteomes; UP000005226; Chromosome 12.
DR   GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12442:SF34; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1; 1.
DR   PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR   Pfam; PF11540; Dynein_IC2; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          466..513
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          154..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   631 AA;  70500 MW;  4D1F7252E0C936ED CRC64;
     MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKESDNQ KKRETTPEDS DLDRKRRETE
     ALLQSIGISP DCCYPLVPTP VSPSKSVSTP SETGSQDSAD GGAASRTTKP TLQWDTDPSV
     LQLQADSELG RRMQRLGASK ITQVDFLPRE MVSYSKETQT PLNEEEDEEM AQVKPGLESE
     QQDDEDSRET KEGRTPGPPL LLTEEERQQI LHSSEFQSFL DCSIRVVERA LAEDGDIFFD
     YGGRDLEDKE GDLGSGSRLA LCRLFYDEHW SKHRVITCLD WSPQYPELLV ASYNNNEDAP
     HEPDGVALVW NIKFKKATPE YIFHCQSPVV SVGFARFHPN LVVGGTYSGQ IVLWDNRSHR
     RTPVQRTPLS AAAHTHPVYC VNVVGTQNAN NLITVSTDGR MCSWSLDMLS QPQETMELVY
     NKSKPVAVTC MAFPTGDVNN YVVGSEEGTV YTASRHGSKA GICEMFEGHQ GPVTGISCHG
     AVGTVDFSHL FITSSFDWTV KLWSTKHNKP LYSFEDNADY VYDVMWSPVH PAMFAAVDGM
     GRLDLWNLNN DTEVPTASVT VEGASALNRV RWSSAGKEVA VGDSEGRVWI YDTGELSATH
     ADDWGRFART LMEIRANQAD GEEEGPMELA P
//