ID A0A674NIL1_TAKRU Unreviewed; 500 AA.
AC A0A674NIL1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=G protein pathway suppressor 1 {ECO:0000313|Ensembl:ENSTRUP00000073121.1};
GN Name=gps1 {ECO:0000313|Ensembl:ENSTRUP00000073121.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000073121.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000073121.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000073121.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN1 family.
CC {ECO:0000256|ARBA:ARBA00008793}.
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DR AlphaFoldDB; A0A674NIL1; -.
DR Ensembl; ENSTRUT00000061030.1; ENSTRUP00000073121.1; ENSTRUG00000013208.3.
DR GeneTree; ENSGT00510000046608; -.
DR InParanoid; A0A674NIL1; -.
DR OMA; IYLQNWA; -.
DR Proteomes; UP000005226; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR048624; CSN1_C.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR019585; Rpn7/CSN1.
DR InterPro; IPR045135; Rpn7_N.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR14145; 26S PROTESOME SUBUNIT 6; 1.
DR PANTHER; PTHR14145:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 1; 1.
DR Pfam; PF21151; CSN1_C; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF10602; RPN7; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 278..440
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 474..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 56674 MW; 9812228C806EE7A9 CRC64;
MHDFWVCCTN KHYDLSLTHV CFAQGSVEPM QIDADPQEDQ QNASESNYIV ENPTLDLEQY
ATSYSGLMRI ERLQFIAEHC PQLRVEALKM ALTFVQRTFN VDTYEEIHRK LTEATREVQG
VPDTVPEGGV APPPLDSAWA ESTRKKALLK LEKLDTDLKN YKGNSIKESI RRGHDDLGDH
YLDCGDLSNA LKCYSRARDY CTSAKHVINM CLNVIKVSVY LQNWSHVLSY VNKAESTPEI
AEQRGERDSQ NQAVLTKLKC AAGLAELASR KYKPAAKCFL QASFDHCDCP ELLSPSNAAV
YGGLCALATF DRQELQRNVI SSSSFKLFLE LEPQIRDIIF KFYESKYASC LKLLDEIKDN
LLLDMYLAPH VRTLYSQIRN RALIQYFSPY VSADMNKMAQ AFNTTVAALE DELTQLILEG
LINARIDSHS KILYARDVDQ RSTTFEKSLH MGKEFQRRAK AMILRAAVLR NQIHVKSPPR
EGSQGELAPA NSQTRMSTNM
//
