ID A0A674NJ36_TAKRU Unreviewed; 554 AA.
AC A0A674NJ36;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Afadin- and alpha-actinin-binding protein-like {ECO:0000313|Ensembl:ENSTRUP00000073108.1};
GN Name=LOC101068419 {ECO:0000313|Ensembl:ENSTRUP00000073108.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000073108.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000073108.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000073108.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the ADIP family.
CC {ECO:0000256|ARBA:ARBA00009291}.
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DR AlphaFoldDB; A0A674NJ36; -.
DR Ensembl; ENSTRUT00000073648.1; ENSTRUP00000073108.1; ENSTRUG00000011160.3.
DR GeneTree; ENSGT00390000007688; -.
DR Proteomes; UP000005226; Chromosome 22.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR021622; Afadin/alpha-actinin-bd.
DR PANTHER; PTHR46507; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR PANTHER; PTHR46507:SF2; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR Pfam; PF11559; ADIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT COILED 115..216
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 375..402
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 554 AA; 63866 MW; E54F1056014C83D8 CRC64;
MGEWWTSVPM VASTEHSEIS SISHLTMSPT RPNNVSLMYP CLPLTKNSYS VISAFCTEDN
IPQCISYINQ ELSSLGLSSP CIGATSAGRP SLNTVLALNA MYEMVQIHRR SMSTLEELEK
EHLKKSSSLE HMQTNNSRLK DQLELSIREK FGLHETERQL QLKIKTLQSC LKTEKDEVQK
LQNIITSRAT QYSHDAKRKE REAAKLKERL SQLLIDRKDK KLAIDVLNSL GRADGKRSHW
KTAKVTARYH EGEMYKSLLS DYEASQRSLM LENSELKKVL QQMKKDMIHI LSPRQASNRG
ACADDSQEQV DLDREEEAGD CCRDTLDQSC EHAREQLTNS IRQQWRKLRN HVEKLDSQAS
QVQNQLQAGK DVIPRETHED EMEEMRREVQ QCKEFIQAQQ QLLQQQLNSS LDDETAAFLN
DCYTLEEKER LKEEWRLFEE QKRNFARERK NFTEAAIRLG REKKAFQEDR DTWLKNQFLN
MTPFTDRRRC SSSDGQSALS ISKSAHTCHV CVTSGGFLSL RWAGGGDARF SSKNRLRCED
LSNFSLDEDE NRLA
//
