ID A0A674P9L0_TAKRU Unreviewed; 599 AA.
AC A0A674P9L0;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Afadin- and alpha-actinin-binding protein-like {ECO:0000313|Ensembl:ENSTRUP00000082339.1};
GN Name=LOC101068419 {ECO:0000313|Ensembl:ENSTRUP00000082339.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000082339.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000082339.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000082339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the ADIP family.
CC {ECO:0000256|ARBA:ARBA00009291}.
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DR AlphaFoldDB; A0A674P9L0; -.
DR Ensembl; ENSTRUT00000065929.1; ENSTRUP00000082339.1; ENSTRUG00000011160.3.
DR GeneTree; ENSGT00390000007688; -.
DR InParanoid; A0A674P9L0; -.
DR OMA; ETAYKAQ; -.
DR OrthoDB; 2963617at2759; -.
DR Proteomes; UP000005226; Chromosome 22.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR021622; Afadin/alpha-actinin-bd.
DR PANTHER; PTHR46507; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR PANTHER; PTHR46507:SF2; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR Pfam; PF11559; ADIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT REGION 484..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 115..216
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 374..401
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 599 AA; 68888 MW; D4FF3AE33FD099C2 CRC64;
MGEWWTSVPM VASTEHSEIS SISHLTMSPT RPNNVSLMYP CLPLTKNSYS VISAFCTEDN
IPQCISYINQ ELSSLGLSSP CIGATSAGRP SLNTVLALNA MYEMVQIHRR SMSTLEELEK
EHLKKSSSLE HMQTNNSRLK DQLELSIREK FGLHETERQL QLKIKTLQSC LKTEKDEVQK
LQNIITSRAT QYSHDAKRKE REAAKLKERL SQLLIDRKDK KLAIDVLNSL GRADGKRSHW
KTAKVTASHE GEMYKSLLSD YEASQRSLML ENSELKKVLQ QMKKDMIHIL SPRQASNRGA
CADDSQEQVD LDREEEAGDC CRDTLDQSCE HAREQLTNSI RQQWRKLRNH VEKLDSQASQ
VQNQLQAGKD VIPRETHEDE MEEMRREVQQ CKEFIQAQQQ LLQQQLNSSL DDETAAFLND
CYTLEEKERL KEEWRLFEEQ KRNFARERKN FTEAAIRLGR EKKAFQEDRD TWLKNQFLNM
TPFTDRRRCS SSDGQSALSI RSEPERRMSS TNAQLATSSS YATFSTPKPT QCTTVPSTAE
LYRTLRLMPD GSSSRHTNRG CWQDSCISEG GDARFSSKNR LRCEDLSNFS LDEDENRLA
//
