ID   A0A674PJL4_TAKRU        Unreviewed;       882 AA.
AC   A0A674PJL4;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Protein bicaudal D homolog 2 {ECO:0000313|Ensembl:ENSTRUP00000085729.1};
GN   Name=BICD2 {ECO:0000313|Ensembl:ENSTRUP00000085729.1};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000085729.1, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000085729.1, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000085729.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the BicD family.
CC       {ECO:0000256|ARBA:ARBA00010061}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A674PJL4; -.
DR   Ensembl; ENSTRUT00000088299.1; ENSTRUP00000085729.1; ENSTRUG00000008866.3.
DR   GeneTree; ENSGT00940000154471; -.
DR   InParanoid; A0A674PJL4; -.
DR   OMA; CACASER; -.
DR   Proteomes; UP000005226; Chromosome 3.
DR   GO; GO:0008093; F:cytoskeletal anchor activity; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   Gene3D; 6.10.250.2470; -; 1.
DR   InterPro; IPR018477; BICD.
DR   PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR   PANTHER; PTHR31233:SF7; PROTEIN BICAUDAL D HOMOLOG 2; 1.
DR   Pfam; PF09730; BicD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   REGION          401..423
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          560..606
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          790..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          54..81
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          118..246
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          437..503
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          681..775
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        402..423
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        803..818
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   882 AA;  100990 MW;  C72ADEFB80F40608 CRC64;
     MSVEEQGYLD AMLLQEARPE WMRAEIERLS RELLETTNEK IQAAEYGLVV LEEKQQLKQQ
     YDDLEIDYEA VRRELDLLKE AFGQAYTNHR KVAADGESRE ESLIQESACK EAYYEQRVLE
     LQNDLRQARN LVSNTQSEND RLNTLSQEMK DHSQMVELQR NQLRDDIKEY KLLEARLLQD
     YTELEEENIS LQKQVSVLKQ SQVEFEGLKH EIRRLEEDTQ FLNSQLEDAI RLKEIAERQL
     GEALETIKTE RELKASLRKE LSHYMNIGDT LPLSISLDGL KFSEDTATEP NNDEALHGYD
     NDFTKLANAI NYDNCVSTPN KELFHPAPSL VDDLLSELNI SEIQKLKQQL MQMEREKVNL
     LTTLQDSQKQ LEQANGALSE HQDKVNRLTE NLNAIRKLQA SKERQSALDN EKERDSHEDG
     DYYEVDINGP EILECKYKVA VSEAGELKEE LKTLKAEYQT CQSRYEDDRA RLESDVTTLG
     EKLASLEKTS HMDREEKNKL ETELRKLRDV AGESQGSLSV AQDELVTFSE ELATLYNHVC
     MCNNETPNRI MLDFYKEGKG VRSSPEGRGR RSPILLTKGL FPEPGKTDLS DRAPSPVSSL
     PSPVSDHRRE PMNIYNLVAI IRDQIKHLQL AVDRTTELSR QRVASLEFGT VADKDKEACM
     EEILKLKSLL STKREQIATL RTVLKANKQT AEVALANLKS KYENEKAMVT ETMMKLRNEL
     KALKEDAATF SSLRAMFATR CDEYVTQLEE MQRQLSAAED EKKTLNSLLR MAIQQKLALT
     QRLEDLEFDH EQVRRGGNSG RSKARSKAPT GTSNGSHVSQ SLTYLHGFAA EDAYRFLFYF
     LKTTVSCCQA CWYKTNACVT GLYAATLAVY VVFSEVQEGY SM
//