ID A0A6A2YIJ8_HIBSY Unreviewed; 1026 AA.
AC A0A6A2YIJ8;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Protein HIRA {ECO:0000256|RuleBase:RU364014};
GN ORFNames=F3Y22_tig00111614pilonHSYRG00047
GN {ECO:0000313|EMBL:KAE8676387.1};
OS Hibiscus syriacus (Rose of Sharon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Hibiscus.
OX NCBI_TaxID=106335 {ECO:0000313|EMBL:KAE8676387.1, ECO:0000313|Proteomes:UP000436088};
RN [1] {ECO:0000313|EMBL:KAE8676387.1, ECO:0000313|Proteomes:UP000436088}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Baekdansim {ECO:0000313|Proteomes:UP000436088};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAE8676387.1};
RA Kim Y.-M.;
RT "Draft genome information of white flower Hibiscus syriacus.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for replication-independent chromatin assembly and
CC for the periodic repression of histone gene transcription during the
CC cell cycle. {ECO:0000256|RuleBase:RU364014}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364014}.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family.
CC {ECO:0000256|ARBA:ARBA00007306, ECO:0000256|RuleBase:RU364014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8676387.1}.
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DR EMBL; VEPZ02001383; KAE8676387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6A2YIJ8; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000436088; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR031120; HIR1-like.
DR InterPro; IPR011494; HIRA-like_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13831; MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; 1.
DR PANTHER; PTHR13831:SF0; PROTEIN HIRA; 1.
DR Pfam; PF07569; Hira; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU364014}; Nucleus {ECO:0000256|RuleBase:RU364014};
KW Reference proteome {ECO:0000313|Proteomes:UP000436088};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364014};
KW Repressor {ECO:0000256|RuleBase:RU364014};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364014};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364014};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 16..44
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 121..162
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 163..204
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 686..883
FT /note="Protein HIRA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07569"
FT REGION 432..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1018
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1026 AA; 112448 MW; 1DADE3AC12FCFB7C CRC64;
MITEKPSWAR HEGMQIFSID IQPGGLRFAT GGGDHKVRVW NMESVGRNLG KDESTLRLLA
TLRDHFGSVN CVRWAKHGRF VASGSDDQVI LIHERKPGSG TTEFGSGESP DVENWKVAMT
LRGHTADVVD LNWSPDDSML ASGSLDNTIH IWNMSNGICT AVLRGHSSLV KGVAWDPIGS
FIASQSDDKT VIIWRTSDWS LAHKTDGHWT KSLGSTFFRR LGWSPCGHFI TTTHGYQKPR
HSAPVLERGE WAATFDFLGH NAPIIAVKFN HSMFRRNSAN SHEVKGTPVG WANGAGKTGE
KESQPYNVIA IGSQDRTITV WTTASPRPLF VAKHFFGQSV VDLSWSPDGY SLFACSLDGT
VATFHFEVKE LGHKLSDAEL DELKRSRYGD VRGRQANLAE SPAQLLLEAA SAKQTTSKKV
ALDVQQNQMP LKSSLELGVS NKSSKPQNSD GKKSRLSSGD GLNKTVTPVR VSSPVKQREY
RRADGRKRII PEVVGVPIHQ ENISGSAQAL DFPVAYSDPR KNNNSVVHAD SSLRETTIRG
TIGRSFDLKE CSGVAARATV TDSLVVEKVS AGQDHSINVE QPGIMKPSGS TVSSTKSLSI
RVFDKKEGDD MTPICLEACP REHAVNDIVG VGNACMTKET EIVCTRGAQT LWSDRISGKV
SVLAGNANFW AVGCEDGCLQ VYTKCGRRAL PTMMIGSAAT FVDCDENWKL LLVTRKGSLY
LWDLFNRNCL LRDSLESLIT LDQRSSTKGT IKVISVKLSK SGFPLVVLAT RHAFLFDANL
MCWLRVADDC FPTSNFASSW NLGSTQTGEL ASLQVDVRKY LARKPGWSRV TDDGVQTRAH
LEAQLTSSLS LKSPNEYRQS LLSYVRFLAR EADESRLREV CESFLGPPTG MASDANNPAW
DAYVLGMEKH KLLREDILPA MASNRKVQRL LNEFMDLLSE YVSVENNVSQ ENPSPTTSRP
EIDRMDSNPS VPGQTDTPAR ATDDKENPSP GIDQMGSIPS MSNQVNSGTE STDQVNRAPI
SEEAAG
//
