ID   A0A6A2YPF1_HIBSY        Unreviewed;      1066 AA.
AC   A0A6A2YPF1;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=RNase H type-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=F3Y22_tig00111338pilonHSYRG00169
GN   {ECO:0000313|EMBL:KAE8681196.1};
OS   Hibiscus syriacus (Rose of Sharon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Hibiscus.
OX   NCBI_TaxID=106335 {ECO:0000313|EMBL:KAE8681196.1, ECO:0000313|Proteomes:UP000436088};
RN   [1] {ECO:0000313|EMBL:KAE8681196.1, ECO:0000313|Proteomes:UP000436088}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Baekdansim {ECO:0000313|Proteomes:UP000436088};
RC   TISSUE=Leaf {ECO:0000313|EMBL:KAE8681196.1};
RA   Kim Y.-M.;
RT   "Draft genome information of white flower Hibiscus syriacus.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAE8681196.1}.
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DR   EMBL; VEPZ02001313; KAE8681196.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6A2YPF1; -.
DR   Proteomes; UP000436088; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   CDD; cd06222; RNase_H_like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR025558; DUF4283.
DR   InterPro; IPR044730; RNase_H-like_dom_plant.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR46890:SF32; NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN; 1.
DR   PANTHER; PTHR46890; NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED; 1.
DR   Pfam; PF14111; DUF4283; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000436088}.
FT   DOMAIN          232..317
FT                   /note="DUF4283"
FT                   /evidence="ECO:0000259|Pfam:PF14111"
FT   DOMAIN          811..898
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|Pfam:PF13456"
FT   REGION          138..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          197..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..175
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..215
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1066 AA;  119964 MW;  D06FF149218C5AB3 CRC64;
     MDSKVIEDQE RVPVARVGIV HVSENPMLIA SAMLPITLCL RTTLPLGSIQ PIATSGLKSG
     TYLGPTKWMQ GLLCDAREGL SVFEMSIHYY AMFLELGCGY QTDILLKSHL NPIFPQCSLK
     SSSSLFIPLT RVVNARRESA GHGSAPGGRR FDRERGGNKR LRPTGGEEPT EERVWTKSWS
     DTVADSPFFT GMFNNSSRVE EEDYESEDEE ELENDGIPSS GSWTRVLCGE ISKHERAKVL
     TDGPWKIMDH YLTVQKWKPN FIAEEALIPS TTVWIHIPGP RMEYFDERVL VNIGKLVGSP
     LKVDCRTAWV TRGTGDKIKK KLQFDESYEV PAQGRHDTGG KSWLNSFVYV QPHGSKKEEF
     WLDMDRLGSN CDCLDRIIRF REQWNRCNLL NAGRTEMIDQ FPNFQVSILP RYYSDHNPIL
     LNMDLKKDSI LEAIKYTSRV IITWKNEAIG NIFKWKRTLR NHLQVDRGSW KAIKLARGGT
     NISHLLFAND LMLFLEARGD QISEVQNCLA EFCQASGLEV NLQKSKKFIS PNVNEGLATR
     IVQLSSISWT EDLGIYLGVP ILHKRENAET FTPLVKKILK KLASWKGKVL SMAGRRTLIQ
     AVTSAIPIHT MQTNILPAAI CNRLDSINQN FVRRRRIGIH KTRVMNLALM AKNGWKMFQR
     KDLLWCKIFR EKYLKQEMYM SIKKRENSSS TWRGILKVRE VIKNGSKHQI RSDEQTDFWQ
     DWWTGKHALV KEYPERENSQ NEKVARFILE NKQWDINNLQ NMVSRDTIDQ IRSTLISWLN
     HEREEDKIVW GHSKDGQFSV KSAFKDPYLM NSNGYAAAGG LIRDEEGNWI QGFMINIGKT
     TSTLAEVWGL RQGLLLAKEM GARNLVVETD AKWLAETLNK EKSEQVQREA ILPDCEELRR
     GMDYRNKAHI EGRGVEEFAS GRQVRDRNVK MLPRQQIHQQ QRQNILESSI QYSNRDMAKY
     CNVVLVLALA VVVVQATSRN VPKDAAGLDD QKNFLTYGGV GGYSGIGADG MPIGGVGSAG
     GTTGLDGTGG TGGISGVGFG NGDDSGAGGG VVGGTGGSAP GVIHFP
//