ID   A0A6A3CVV9_HIBSY        Unreviewed;       502 AA.
AC   A0A6A3CVV9;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 9.
DE   RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN   Name=MLO {ECO:0000256|RuleBase:RU280816};
GN   ORFNames=F3Y22_tig00002840pilonHSYRG01341
GN   {ECO:0000313|EMBL:KAE8731438.1};
OS   Hibiscus syriacus (Rose of Sharon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Hibiscus.
OX   NCBI_TaxID=106335 {ECO:0000313|EMBL:KAE8731438.1, ECO:0000313|Proteomes:UP000436088};
RN   [1] {ECO:0000313|EMBL:KAE8731438.1, ECO:0000313|Proteomes:UP000436088}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Baekdansim {ECO:0000313|Proteomes:UP000436088};
RC   TISSUE=Leaf {ECO:0000313|EMBL:KAE8731438.1};
RA   Kim Y.-M.;
RT   "Draft genome information of white flower Hibiscus syriacus.";
RL   Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC       cell death. {ECO:0000256|RuleBase:RU280816}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC   -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC       binds calmodulin in a calcium-dependent fashion.
CC       {ECO:0000256|RuleBase:RU280816}.
CC   -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC       ECO:0000256|RuleBase:RU280816}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAE8731438.1}.
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DR   EMBL; VEPZ02000196; KAE8731438.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6A3CVV9; -.
DR   Proteomes; UP000436088; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   InterPro; IPR004326; Mlo.
DR   PANTHER; PTHR31942:SF82; MLO PROTEIN HOMOLOG 1; 1.
DR   PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR   Pfam; PF03094; Mlo; 2.
PE   3: Inferred from homology;
KW   Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW   Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW   Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW   ECO:0000256|RuleBase:RU280816};
KW   Plant defense {ECO:0000256|RuleBase:RU280816};
KW   Reference proteome {ECO:0000313|Proteomes:UP000436088};
KW   Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        17..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        141..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          384..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..438
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        454..476
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   502 AA;  56639 MW;  32AE1647373DEB44 CRC64;
     MAGNYRKERS LEETPTWAVA VVCAIFVIIS ILIEHGIHSL GKWFQKRQKK AMMEALEKIK
     AELMLLGFIS LLLTIGTYSI PAICIPEKIG YSMLPCERKS VYGGDGDKGS SKGMTLVTAA
     GGSYFLMGKV ALISQSGMHD LHIFIFALAV FHVLYSVATI FLAKAKMKKW EAWESETKTL
     EYQYTNGISS PIDLDFWINT SNFLRETSFW FLRNSRHQWI VAFFRQFFGS VSKVDYLTMR
     NGFINAHFAA NTSFDFHKYI KRSMEDDFKV VVGIRMANSQ LAVTSPLDVG TKLEVIIMDM
     AEEIQERSAV VRGAPVVEPN NKYFWFNRPQ WILFLIHYTL FQNAFQMAYF LWVWGSPWGV
     PSNSMQLHYL PTLCFGDPDG VSHEINIRGA DSQGSKELAQ GCQEEKQEQS KREGSAGMNS
     HASPSMSVDS TPSRGTSPLH LLHNHKHRST AACDQTDGVL NSPTHSNYSY PSDTEISDIE
     AFSPRPRHAT PPLDHQHQTP TT
//