ID A0A6A6MVN1_HEVBR Unreviewed; 983 AA.
AC A0A6A6MVN1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=GH714_012179 {ECO:0000313|EMBL:KAF2317147.1};
OS Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Micrandreae;
OC Hevea.
OX NCBI_TaxID=3981 {ECO:0000313|EMBL:KAF2317147.1, ECO:0000313|Proteomes:UP000467840};
RN [1] {ECO:0000313|EMBL:KAF2317147.1, ECO:0000313|Proteomes:UP000467840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. GT1 {ECO:0000313|Proteomes:UP000467840};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF2317147.1};
RX PubMed=31838037; DOI=10.1016/j.molp.2019.10.017;
RA Liu J., Shi C., Shi C.C., Li W., Zhang Q.J., Zhang Y., Li K., Lu H.F.,
RA Shi C., Zhu S.T., Xiao Z.Y., Nan H., Yue Y., Zhu X.G., Wu Y., Hong X.N.,
RA Fan G.Y., Tong Y., Zhang D., Mao C.L., Liu Y.L., Hao S.J., Liu W.Q.,
RA Lv M.Q., Zhang H.B., Liu Y., Hu-Tang G.R., Wang J.P., Wang J.H., Sun Y.H.,
RA Ni S.B., Chen W.B., Zhang X.C., Jiao Y.N., Eichler E.E., Li G.H., Liu X.,
RA Gao L.Z.;
RT "The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge
RT Genome Evolution and Rubber Biosynthesis.";
RL Mol. Plant 13:336-350(2020).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF2317147.1}.
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DR EMBL; JAAGAX010000004; KAF2317147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6A6MVN1; -.
DR Proteomes; UP000467840; Chromosome 6.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR026960; RVT-Znf.
DR PANTHER; PTHR33710; BNAC02G09200D PROTEIN; 1.
DR PANTHER; PTHR33710:SF61; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF00481; PP2C; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF13966; zf-RVT; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000467840}.
FT DOMAIN 827..983
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 983 AA; 111999 MW; 548376B5F43C9A21 CRC64;
MLGEWRITGF YGRPNRNERR ASWALLRELA SQYSYPWVCC GDFNAILTQD EKRGGNFYPT
YLVQDFRDAV LQAGLSDVNM NGYKYTWDNA RDDDDWVEAK LDRFLANDDW KRRFALSKAA
VLDYSSSDHL PILLQVRIFL PRHSPRLFRF ENTWGAESGC REIVEEIWSD PSLGSVLEKL
QFCSVRLGEW GDNLRKLYKQ EIDDCKRVMG LLRGKRDAHS RESFRMAKSK FLDLLRRKES
YWRQRAKEFW LKEGDQNTKF FHRKATIRQR KNRIDRLKDD NGNWCDWSTG LEAMITDYFK
NIFTSNAGSS NDIIDLVPAL VTDDQNVDLM KPWLPDVAFP MVTTTFDFNF GVYMVSDLIT
DGAWNIDLVN RVFNERDRKL ILSIPLRRSS SIDLQFWKHD KRGSYSVSSA YKLQTQESDT
AVGNKKFWKK LWSIPAAPKI RNFLWRAVSG SLPTRSRLCS RHVPTTEVCP LCNVDCESVK
HVLVECSFAR HVWLASHLGW FSPSTHSFQD WLMRALALFN PNDSATLAYL CWSIWEERNS
VVWKSAQPAA NSCRLRGLRL KREWDDALVS IRAAIPPTAD LPTPQEWKKP GPNWVKLNVD
IATNVNSGWT GIGMVVRNEM GSFVACKISR MVGLFSPTIA EIMGVREALS WIKDNNWQNV
IVESDNLQVV NVLNSMNVEN FSMMGGIVSD CRSLINEISC EILFSHVFRS ANGVAHALAQ
ATRSFPNAME WTLSPPEFDA KQVNQEVESL GNTNINKKQS WPLHCEALHD KMDNWDKDSS
LISSSDGISV CSSFPTFGAI QLESICEDRV TLERKQNLAT NFIPVLRSGE WSDIGGRLYM
EDTHICIGDL AKKFGYNLLR EESVSFYGVF DGHGGKSAAH FVRDHLPRVI VEDADFALEL
EKVVARSFIE TDTAFAETCS LESSLSSGTT AITALIFGSS LLVANAGDCR AVLSRRGTAI
EMSKDHRPCC VNERTRIESR GIC
//
