ID A0A6B2UV08_9ACTN Unreviewed; 634 AA.
AC A0A6B2UV08;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:NEA44878.1};
GN ORFNames=G3I35_00850 {ECO:0000313|EMBL:NEA44878.1};
OS Streptomyces sp. SID10815.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2706027 {ECO:0000313|EMBL:NEA44878.1, ECO:0000313|Proteomes:UP000481022};
RN [1] {ECO:0000313|EMBL:NEA44878.1, ECO:0000313|Proteomes:UP000481022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SID10815 {ECO:0000313|EMBL:NEA44878.1,
RC ECO:0000313|Proteomes:UP000481022};
RA Currrie C., Chevrette M., Carlson C., Stubbendieck R., Wendt-Pienkowski E.;
RT "Insect and environment-associated Actinomycetes.";
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NEA44878.1}.
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DR EMBL; JAAGLM010000043; NEA44878.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6B2UV08; -.
DR Proteomes; UP000481022; Unassembled WGS sequence.
DR GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR InterPro; IPR029229; Alkyl_sulf_C.
DR InterPro; IPR029228; Alkyl_sulf_dimr.
DR InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR PANTHER; PTHR43223:SF1; ALKYL_ARYL-SULFATASE BDS1; 1.
DR Pfam; PF14864; Alkyl_sulf_C; 1.
DR Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:NEA44878.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000481022};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 105..326
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 634 AA; 68937 MW; F844C4D02DA1CA64 CRC64;
MLQDSGAEPA EPGVVAANAE VRRRFAFDDT QDLDDARRGF MGTAPESLIR AEDGRVVWDL
DAYGFLDQDC PDTANPSLWR QSRLCSEHGL FEVTEGIYQV RGFDLSNMTL VEGERGVFVI
DPLLCAETAA AGLALYRAHR GERPVTGVLY THSHADHFGG VRGVLGDEDV ARGAPVLAPH
GFLEHAVSEN VYAGTAMNRR AAYMYGAALP KGERGQIGAG LGQTTATGSV GLIPPTVDIT
RTGQSETVDG IRMVFQLTPG TEAPAELNLH FPDRAALCMA ENATHNLHNL LTLRGAQVRD
PRVWARYLAE AVALYGASSD VAFASHHWPV WGRERVVAFL TGQRDLYAYL HDQTLRLLNQ
GRTALEIAEE IRLPPALERA WHTHGYYGSV SHNTKAVYQR YLGWFDGNPA HLWEHPPVEA
ARRYVEFMGG ADEVVRRARR SFADGDFRWV AQVVQHVLFA DPDHAEARRL QADALEQLGY
GSENGTWRNF FLTGAHELRH GSVGTPTATT SPDLLAALTI DQLFDSLAIR VDGPRCWDAD
IAVRFEITGG GATTLWLRNG VLTHGADTGT GADADLDVTI ALPESDLRAL LLGATNPADL
AARENVRVTG DLGGLTALLG HLDAPDPDFA IVVP
//
