ID   A0A6B3HBW8_9ACTN        Unreviewed;       372 AA.
AC   A0A6B3HBW8;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=ACR3 family arsenite efflux transporter {ECO:0000313|EMBL:NEE49415.1};
GN   Name=arsB {ECO:0000313|EMBL:NEE49415.1};
GN   ORFNames=G3M55_33015 {ECO:0000313|EMBL:NEE49415.1};
OS   Streptomyces sp. SID8455.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2706104 {ECO:0000313|EMBL:NEE49415.1, ECO:0000313|Proteomes:UP000481552};
RN   [1] {ECO:0000313|EMBL:NEE49415.1, ECO:0000313|Proteomes:UP000481552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SID8455 {ECO:0000313|EMBL:NEE49415.1,
RC   ECO:0000313|Proteomes:UP000481552};
RA   Currrie C., Chevrette M., Carlson C., Stubbendieck R., Wendt-Pienkowski E.;
RT   "Insect and environment-associated Actinomycetes.";
RL   Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:NEE49415.1}.
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DR   EMBL; JAAGND010004327; NEE49415.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6B3HBW8; -.
DR   Proteomes; UP000481552; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000481552};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        32..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   372 AA;  39949 MW;  924988D93B42E64E CRC64;
     MTPTESTAAP AEGAGPARDD SIVKKLSTLD RYLAVWILIA MAVGLGLGRA IPGLNDALAK
     VEIGGISLPI ALGLLIMMYP VLAKVHYDKL DAVTGDRRLM ISSLVINWIL GPAVMFALAW
     IFLPDLPEYR TGLIIVGLAR CIAMVIIWND LARGDREAAA VLVALNSVFQ VIAFGLLGWF
     YLDLLPGWLG LGDGEHLDIS MWEIALNVVI FLGVPLLAGF LTRRVGEKKM GREDYEQRFL
     PKIGPWALYG LLFTIVILFA LQGKTITSQP LDVARIALPL LVYFAVMFFG TFPLGKGLGL
     AYDRTTTLAF TAAGNNFELA IAVAIATFGV TSGQALSGVV GPLIEVPVLI GLVYVALAWR
     RKFAPGAVTT AP
//