ID A0A6G0IPR0_LARCR Unreviewed; 792 AA.
AC A0A6G0IPR0;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=DnaJ homolog subfamily C member 16 {ECO:0000256|ARBA:ARBA00020921};
DE AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 8 {ECO:0000256|ARBA:ARBA00035043};
GN ORFNames=D5F01_LYC08309 {ECO:0000313|EMBL:KAE8293206.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KAE8293206.1, ECO:0000313|Proteomes:UP000424527};
RN [1] {ECO:0000313|EMBL:KAE8293206.1, ECO:0000313|Proteomes:UP000424527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMULYC20181020 {ECO:0000313|EMBL:KAE8293206.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAE8293206.1};
RA Xiao S.;
RT "Chromosome genome assembly for large yellow croaker.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays an important role in regulating the size of
CC autophagosomes during the formation process.
CC {ECO:0000256|ARBA:ARBA00035002}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8293206.1}.
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DR EMBL; REGW02000008; KAE8293206.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6G0IPR0; -.
DR Proteomes; UP000424527; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd02963; TRX_DnaJ; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR043361; DNAJC16_TRX.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR44303; DNAJ HOMOLOG SUBFAMILY C MEMBER 16; 1.
DR PANTHER; PTHR44303:SF2; DNAJ HOMOLOG SUBFAMILY C MEMBER 16; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000424527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..792
FT /note="DnaJ homolog subfamily C member 16"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5026343996"
FT TRANSMEM 535..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..95
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 559..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..591
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 90742 MW; 8F2E5077F086569C CRC64;
MAGERMSVQL AVVVVLSVLL TGATHAGPEM DPYKILGVTR SASQAEIKKV YKRLAKEWHP
DKNKNPGAED MFIKITKSYE ILSNEDKRAN YDRYGQTDDT QPYGGSRHGH RHDSFYFDES
FFNFPFNSKN HRDFADSKYI LHFNQYVNDV VPDSYKRPYL IKITSDWCFS CIHIEPVWKE
VVQEMETLGV GIGVVDVGYE RRLANHLGAH RTPSILGVIN GKVTFFHYAV AKEHLRQFVE
DLLPQRLVER VTDTNDLQFL NSWHELNKPH VLLFDQVPVV PLLYKLTAFA YKDYLQFGYV
DQGLSETANL QKQFNINTYA PTMLVFKENT DNPADIIQAK GMKKQIIDEF MANNKFLLVP
RLVNQKLFDE LCPVKQFHRR RKYCVLLITG DEETFSFGNQ AFLSFASTNA REVVRFAYVY
QRLQQPLCDI LMQNKDSEQS PTQVVILERR NAAGKAFFKP VTAWNGSEED KQRLLEELQR
LQKDPSILIH DAMLPELNNE FASMFVIRWI YASYDYLSEV IDDILHNNWR EMMPLLSLIF
SALFILFGTV VIQAFSDSSD DKQTKPKAKD GTKAENGSPG TGSSSSSRPP KKNFVEVTEL
TDITYMSNLV KLRPGHMNIV LVLTDASKNI LLSKFAKEVY SFTGSLTLHF SFLNIDKHSQ
WMNTLLEYAQ DATQIDADED DGGNHKMDYT GYVLALNGHK KYLCLFKPVY TGEDLEGKSS
EDEGSTSGGR SRSSSRDDHP SRKSNRSRSI STLQIHHKLD RLGLWMERLM EGTLPRYYIP
AWPGLDKITP SK
//
