ID A0A6G0IUZ5_LARCR Unreviewed; 262 AA.
AC A0A6G0IUZ5;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Claudin-8 {ECO:0000313|EMBL:KAE8295101.1};
GN ORFNames=D5F01_LYC06027 {ECO:0000313|EMBL:KAE8295101.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KAE8295101.1, ECO:0000313|Proteomes:UP000424527};
RN [1] {ECO:0000313|EMBL:KAE8295101.1, ECO:0000313|Proteomes:UP000424527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMULYC20181020 {ECO:0000313|EMBL:KAE8295101.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAE8295101.1};
RA Xiao S.;
RT "Chromosome genome assembly for large yellow croaker.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the claudin family.
CC {ECO:0000256|ARBA:ARBA00008295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8295101.1}.
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DR EMBL; REGW02000006; KAE8295101.1; -; Genomic_DNA.
DR RefSeq; XP_010734630.2; XM_010736328.2.
DR AlphaFoldDB; A0A6G0IUZ5; -.
DR GeneID; 104923281; -.
DR KEGG; lco:104923281; -.
DR CTD; 445278; -.
DR OrthoDB; 4040914at2759; -.
DR Proteomes; UP000424527; Unassembled WGS sequence.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR006187; Claudin.
DR InterPro; IPR017974; Claudin_CS.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR12002; CLAUDIN; 1.
DR PANTHER; PTHR12002:SF24; CLAUDIN-8; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01077; CLAUDIN.
DR PROSITE; PS01346; CLAUDIN; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000424527};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 262 AA; 29119 MW; 7B2BE2381CD72378 CRC64;
MANSALEIVG LLVTIIGLIG AAASTGMPMW RVTAFIGENI IVFETRYEGL WMNCFRQADI
RMQCKVYDSL LALPPDLQAA RGLMCCALAL GGLGLLISLV GLQCTSCIEN NDRAKRFVLI
IAGVMIIMAC ICVIIPVSWT GHVIIRDFYN PLLIDAQRRE LGEALYIGWV ASAFLFFGGC
MFVCCNLQSE EKGSERYMYS TASDYIPYPP QPLQPMQPLQ PQQLVLLPQP QPRPQPMLSR
HPSTNYSYHS RYPSVRSGVA YL
//
